TY - JOUR
T1 - Recommendations for the diagnosis of pediatric tuberculosis
AU - Chiappini, Elena
AU - Vecchio, A. L O
AU - Garazzino, Silvia
AU - Marseglia, Gianluigi
AU - Bernardi, F.
AU - Castagnola, Elio
AU - Tomà, Paolo
AU - Cirillo, Daniela Maria
AU - Russo, Cristina
AU - Gabiano, Clara
AU - Ciofi, D.
AU - Losurdo, Giuseppe
AU - Bocchino, M.
AU - Tortoli, Enrico
AU - Tadolini, Marina
AU - Villani, Alberto
AU - Guarino, A.
AU - Esposito, Susanna
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Tuberculosis (TB) is still the world’s second most frequent cause of death due to infectious diseases after HIV infection, and this has aroused greater interest in identifying and managing exposed subjects, whether they are simply infected or have developed one of the clinical variants of the disease. Unfortunately, not even the latest laboratory techniques are always successful in identifying affected children because they are more likely to have negative cultures and tuberculin skin test results, equivocal chest X-ray findings, and atypical clinical manifestations than adults. Furthermore, they are at greater risk of progressing from infection to active disease, particularly if they are very young. Consequently, pediatricians have to use different diagnostic strategies that specifically address the needs of children. This document describes the recommendations of a group of scientific societies concerning the signs and symptoms suggesting pediatric TB, and the diagnostic approach towards children with suspected disease.
AB - Tuberculosis (TB) is still the world’s second most frequent cause of death due to infectious diseases after HIV infection, and this has aroused greater interest in identifying and managing exposed subjects, whether they are simply infected or have developed one of the clinical variants of the disease. Unfortunately, not even the latest laboratory techniques are always successful in identifying affected children because they are more likely to have negative cultures and tuberculin skin test results, equivocal chest X-ray findings, and atypical clinical manifestations than adults. Furthermore, they are at greater risk of progressing from infection to active disease, particularly if they are very young. Consequently, pediatricians have to use different diagnostic strategies that specifically address the needs of children. This document describes the recommendations of a group of scientific societies concerning the signs and symptoms suggesting pediatric TB, and the diagnostic approach towards children with suspected disease.
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U2 - 10.1007/s10096-015-2507-6
DO - 10.1007/s10096-015-2507-6
M3 - Article
VL - 35
SP - 1
EP - 18
JO - European Journal of Clinical Microbiology and Infectious Diseases
JF - European Journal of Clinical Microbiology and Infectious Diseases
SN - 0934-9723
IS - 1
ER -