Indicazioni per la misura delle principali proteine sieriche

Translated title of the contribution: Recommendations for the measurement of the most important plasma proteins

Maria Stella Graziani, Anna Caldini, Umberto Basile, Alberto Dolci, Simona Ferraro, Ilaria Ferrarotti, Ilenia Infusino, Maria Teresa Muratore, Michele Mussap, Laura Obici, Paola Pezzati, Giuseppe Previtali, Dominika Szoke, Alessandro Terreni, Martina Zaninotto, Giampaolo Merlini

Research output: Contribution to journalArticle

Abstract

This document, prepared on behalf of the SIBioC Protein Working Group, reviews the existing evidence for recommending the measurement of the most important plasma proteins. For each protein, the related chapter includes: a) a brief introduction describing main biological characteristics, b) the presentation of the available evidence, based on retrieved meta-analyses, systematic reviews, and international and national guidelines, and c) recommendations for the test ordering. The scientific evidence was searched on electronic databases (Medline, Cochrane's database of systematic reviews) and on the websites of scientific societies. Recommendations were classified on the basis of the source of the retrieved evidence as follows: (+++) official National or International guidelines, (++) meta-analyses or systematic reviews, (±) expert opinions and/or clinical practice, and (-) none (not recommended). The following proteins were considered in the paper: albumin, α 1-antitripsin, α 1-acid glycoprotein, α 2-macroglobulin, haptoglobin, β 2- microglobulin, C-reactive protein (both as marker of inflammation and cardiovascular risk), ceruloplasmin, cystatin C, complement factors, rheumatoid factor, ferritin, immunoglobulins (IgA, IgG, IgM, IgD), free light chains, retinol binding protein, soluble transferrin receptor, serum amyloid A, transferrin, and transtyretin.

Original languageItalian
Pages (from-to)244-267
Number of pages24
JournalBiochimica Clinica
Volume36
Issue number4
Publication statusPublished - Aug 2012

Fingerprint

Blood Proteins
Meta-Analysis
Databases
Guidelines
Serum Amyloid A Protein
Cystatin C
Immunoglobulin D
Retinol-Binding Proteins
Macroglobulins
Proteins
Ceruloplasmin
Transferrin Receptors
Haptoglobins
Rheumatoid Factor
Expert Testimony
Transferrin
Ferritins
C-Reactive Protein
Immunoglobulin A
Immunoglobulin M

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical
  • Medical Laboratory Technology

Cite this

Graziani, M. S., Caldini, A., Basile, U., Dolci, A., Ferraro, S., Ferrarotti, I., ... Merlini, G. (2012). Indicazioni per la misura delle principali proteine sieriche. Biochimica Clinica, 36(4), 244-267.

Indicazioni per la misura delle principali proteine sieriche. / Graziani, Maria Stella; Caldini, Anna; Basile, Umberto; Dolci, Alberto; Ferraro, Simona; Ferrarotti, Ilaria; Infusino, Ilenia; Muratore, Maria Teresa; Mussap, Michele; Obici, Laura; Pezzati, Paola; Previtali, Giuseppe; Szoke, Dominika; Terreni, Alessandro; Zaninotto, Martina; Merlini, Giampaolo.

In: Biochimica Clinica, Vol. 36, No. 4, 08.2012, p. 244-267.

Research output: Contribution to journalArticle

Graziani, MS, Caldini, A, Basile, U, Dolci, A, Ferraro, S, Ferrarotti, I, Infusino, I, Muratore, MT, Mussap, M, Obici, L, Pezzati, P, Previtali, G, Szoke, D, Terreni, A, Zaninotto, M & Merlini, G 2012, 'Indicazioni per la misura delle principali proteine sieriche', Biochimica Clinica, vol. 36, no. 4, pp. 244-267.
Graziani MS, Caldini A, Basile U, Dolci A, Ferraro S, Ferrarotti I et al. Indicazioni per la misura delle principali proteine sieriche. Biochimica Clinica. 2012 Aug;36(4):244-267.
Graziani, Maria Stella ; Caldini, Anna ; Basile, Umberto ; Dolci, Alberto ; Ferraro, Simona ; Ferrarotti, Ilaria ; Infusino, Ilenia ; Muratore, Maria Teresa ; Mussap, Michele ; Obici, Laura ; Pezzati, Paola ; Previtali, Giuseppe ; Szoke, Dominika ; Terreni, Alessandro ; Zaninotto, Martina ; Merlini, Giampaolo. / Indicazioni per la misura delle principali proteine sieriche. In: Biochimica Clinica. 2012 ; Vol. 36, No. 4. pp. 244-267.
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