Recommendations for the routine use of pancreatic amylase measurement instead of total amylase for the diagnosis and monitoring of pancreatic pathology

Mauro Panteghini; Ferruccio Ceriotti; Franca Pagani; Sandra Secchiero; Martina Zaninotto; Carlo Franzini

doi:10.1515/CCLM.2002.017

Recommendations for the routine use of pancreatic amylase measurement instead of total amylase for the diagnosis and monitoring of pancreatic pathology

Mauro Panteghini, Ferruccio Ceriotti, Franca Pagani, Sandra Secchiero, Martina Zaninotto, Carlo Franzini

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

This document reviews the scientific evidence expected to persuade clinical laboratories to substitute pancreatic amylase measurement for total amylase in cases of suspected pancreatic pathology. A substantial evidence is now available to support such change. The measurement of pancreatic amylase in serum is: 1. more sensitive and specific for the detection of pancreatic tissue damage than that of the total enzyme activity, 2. easy and quick to perform in emergency conditions, 3. analytically precise in relation to its clinical application, 4. suitable for easy transfer and comparison of results from different care delivery units, and 5. characterized by well-defined decision limits for the diagnosis of acute pancreatitis.

Original language	English
Pages (from-to)	97-100
Number of pages	4
Journal	Clinical Chemistry and Laboratory Medicine
Volume	40
Issue number	2
DOIs	https://doi.org/10.1515/CCLM.2002.017
Publication status	Published - 2002

Keywords

Amylase
Isoenzymes
Pancreatitis

ASJC Scopus subject areas

Clinical Biochemistry

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10.1515/CCLM.2002.017

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Recommendations for the routine use of pancreatic amylase measurement instead of total amylase for the diagnosis and monitoring of pancreatic pathology. / Panteghini, Mauro; Ceriotti, Ferruccio; Pagani, Franca; Secchiero, Sandra; Zaninotto, Martina; Franzini, Carlo.

In: Clinical Chemistry and Laboratory Medicine, Vol. 40, No. 2, 2002, p. 97-100.

Research output: Contribution to journal › Article › peer-review

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abstract = "This document reviews the scientific evidence expected to persuade clinical laboratories to substitute pancreatic amylase measurement for total amylase in cases of suspected pancreatic pathology. A substantial evidence is now available to support such change. The measurement of pancreatic amylase in serum is: 1. more sensitive and specific for the detection of pancreatic tissue damage than that of the total enzyme activity, 2. easy and quick to perform in emergency conditions, 3. analytically precise in relation to its clinical application, 4. suitable for easy transfer and comparison of results from different care delivery units, and 5. characterized by well-defined decision limits for the diagnosis of acute pancreatitis.",

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AU - Zaninotto, Martina

AU - Franzini, Carlo

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Recommendations for the routine use of pancreatic amylase measurement instead of total amylase for the diagnosis and monitoring of pancreatic pathology

Abstract

Keywords

ASJC Scopus subject areas

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