Recommendations for the use of biologic (TNF-α blocking) agents in the treatment of rheumatoid arthritis in Italy

Guido Valesini, Carlomaurizio Montecucco, Maurizio Cutolo

Research output: Contribution to journalArticle

Abstract

The present report is devoted to drawing up and disseminating specific recommendations for the use of anti-TNF-α therapies in patients with rheumatoid arthritis (RA) in Italy. The document reports and discusses the published literature concerning the criteria for inclusion, assessment of response and for withdrawal of treatment with TNF blocking agents in RA. Several specific points concerning more sensitive warnings are discussed: tuberculosis, hepatitis, lymphoma, and cardiovascular risk and induction of autoimmunity. The recommendations are summarized in an 8-point table approved by the executive committee of the Italian Societyfor Rheumatology.

Original languageEnglish
Pages (from-to)413-423
Number of pages11
JournalClinical and Experimental Rheumatology
Volume24
Issue number4
Publication statusPublished - Jul 2006

Keywords

  • Anti-TNF
  • Biological agents
  • Management
  • Recommendations
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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