Recommended Screening and Preventive Practices for Long-Term Survivors after Hematopoietic Cell Transplantation

Navneet S. Majhail, J. Douglas Rizzo, Stephanie J. Lee, Mahmoud Aljurf, Yoshiko Atsuta, Carmem Bonfim, Linda J. Burns, Naeem Chaudhri, Stella Davies, Shinichiro Okamoto, Adriana Seber, Gerard Socie, Jeff Szer, Maria Teresa van Lint, John R. Wingard, Andre Tichelli

Research output: Contribution to journalArticle

Abstract

Advances in hematopoietic cell transplantation (HCT) technology and supportive care techniques have led to improvements in long-term survival after HCT. Emerging indications for transplantation, introduction of newer graft sources (eg, umbilical cord blood) and transplantation of older patients using less intense conditioning regimens have also contributed to an increase in the number of HCT survivors. These survivors are at risk for developing late complications secondary to pre-, peri-, and posttransplantation exposures and risk factors. Guidelines for screening and preventive practices for HCT survivors were published in 2006. An international group of transplantation experts was convened in 2011 to review contemporary literature and update the recommendations while considering the changing practice of transplantation and international applicability of these guidelines. This review provides the updated recommendations for screening and preventive practices for pediatric and adult survivors of autologous and allogeneic HCT.

Original languageEnglish
Pages (from-to)348-371
Number of pages24
JournalBiology of Blood and Marrow Transplantation
Volume18
Issue number3
DOIs
Publication statusPublished - Mar 2012

Keywords

  • Allogeneic
  • Autologous
  • Hematopoietic cell transplantation
  • Late complications
  • Prevention
  • Screening

ASJC Scopus subject areas

  • Transplantation
  • Hematology

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  • Cite this

    Majhail, N. S., Rizzo, J. D., Lee, S. J., Aljurf, M., Atsuta, Y., Bonfim, C., Burns, L. J., Chaudhri, N., Davies, S., Okamoto, S., Seber, A., Socie, G., Szer, J., van Lint, M. T., Wingard, J. R., & Tichelli, A. (2012). Recommended Screening and Preventive Practices for Long-Term Survivors after Hematopoietic Cell Transplantation. Biology of Blood and Marrow Transplantation, 18(3), 348-371. https://doi.org/10.1016/j.bbmt.2011.12.519