Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: A long-term study

G. Dalla Pozza; A. Ghirlando; F. Busato; Edoardo Midena

Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: A long-term study

G. Dalla Pozza, A. Ghirlando, F. Busato, Edoardo Midena

Fondazione G.B. Bietti

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE. To evaluate, on a long- term basis, the role of amniotic membrane in the reconstruction of large conjunctival defects after excision of large conjunctival melanoma. METHODS. Four consecutive patients with diffuse conjunctival melanoma involving both bulbar and palpebral conjunctiva were studied. Conjunctival melanoma was completely excised (with wide clinically disease-free margins) and amniotic membrane immediately sutured to the surrounding conjunctiva and sciera to cover the conjunctival defect. Minimum follow-up was 48 months. RESULTS. Successful conjunctival surface reconstruction and physiologic fornical depth were achieved in all patients within 6 weeks. No recurrence of primary melanoma was observed during long-term follow-up. CONCLUSIONS. Amniotic membrane transplantation is an effective alternative in ocular surface repairing surgery after removal of large conjunctival tumors.

Original language	English
Pages (from-to)	446-450
Number of pages	5
Journal	European Journal of Ophthalmology
Volume	15
Issue number	4
Publication status	Published - Jul 2005

Keywords

Amniotic membrane
Conjunctival melanoma
Primary acquired melanosis

ASJC Scopus subject areas

Ophthalmology

Access to Document

Fingerprint Dive into the research topics of 'Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: A long-term study'. Together they form a unique fingerprint.

Cite this

@article{c81649a039914da0988737f80a8e68df,

title = "Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: A long-term study",

abstract = "PURPOSE. To evaluate, on a long- term basis, the role of amniotic membrane in the reconstruction of large conjunctival defects after excision of large conjunctival melanoma. METHODS. Four consecutive patients with diffuse conjunctival melanoma involving both bulbar and palpebral conjunctiva were studied. Conjunctival melanoma was completely excised (with wide clinically disease-free margins) and amniotic membrane immediately sutured to the surrounding conjunctiva and sciera to cover the conjunctival defect. Minimum follow-up was 48 months. RESULTS. Successful conjunctival surface reconstruction and physiologic fornical depth were achieved in all patients within 6 weeks. No recurrence of primary melanoma was observed during long-term follow-up. CONCLUSIONS. Amniotic membrane transplantation is an effective alternative in ocular surface repairing surgery after removal of large conjunctival tumors.",

keywords = "Amniotic membrane, Conjunctival melanoma, Primary acquired melanosis",

author = "{Dalla Pozza}, G. and A. Ghirlando and F. Busato and Edoardo Midena",

year = "2005",

month = jul,

language = "English",

volume = "15",

pages = "446--450",

journal = "European Journal of Ophthalmology",

issn = "1120-6721",

publisher = "Wichtig Publishing",

number = "4",

}

TY - JOUR

T1 - Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma

T2 - A long-term study

AU - Dalla Pozza, G.

AU - Ghirlando, A.

AU - Busato, F.

AU - Midena, Edoardo

PY - 2005/7

Y1 - 2005/7

N2 - PURPOSE. To evaluate, on a long- term basis, the role of amniotic membrane in the reconstruction of large conjunctival defects after excision of large conjunctival melanoma. METHODS. Four consecutive patients with diffuse conjunctival melanoma involving both bulbar and palpebral conjunctiva were studied. Conjunctival melanoma was completely excised (with wide clinically disease-free margins) and amniotic membrane immediately sutured to the surrounding conjunctiva and sciera to cover the conjunctival defect. Minimum follow-up was 48 months. RESULTS. Successful conjunctival surface reconstruction and physiologic fornical depth were achieved in all patients within 6 weeks. No recurrence of primary melanoma was observed during long-term follow-up. CONCLUSIONS. Amniotic membrane transplantation is an effective alternative in ocular surface repairing surgery after removal of large conjunctival tumors.

AB - PURPOSE. To evaluate, on a long- term basis, the role of amniotic membrane in the reconstruction of large conjunctival defects after excision of large conjunctival melanoma. METHODS. Four consecutive patients with diffuse conjunctival melanoma involving both bulbar and palpebral conjunctiva were studied. Conjunctival melanoma was completely excised (with wide clinically disease-free margins) and amniotic membrane immediately sutured to the surrounding conjunctiva and sciera to cover the conjunctival defect. Minimum follow-up was 48 months. RESULTS. Successful conjunctival surface reconstruction and physiologic fornical depth were achieved in all patients within 6 weeks. No recurrence of primary melanoma was observed during long-term follow-up. CONCLUSIONS. Amniotic membrane transplantation is an effective alternative in ocular surface repairing surgery after removal of large conjunctival tumors.

KW - Amniotic membrane

KW - Conjunctival melanoma

KW - Primary acquired melanosis

UR - http://www.scopus.com/inward/record.url?scp=23844437304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23844437304&partnerID=8YFLogxK

M3 - Article

C2 - 16001375

AN - SCOPUS:23844437304

VL - 15

SP - 446

EP - 450

JO - European Journal of Ophthalmology

JF - European Journal of Ophthalmology

SN - 1120-6721

IS - 4

ER -