Recovery from aphasia and neglect after subcortical stroke

neuropsychological and cerebral perfusion study

Giuseppe Vallar, Daniela Perani, Stefano F. Cappa, Cristina Messa, Gian Luigi Lenzi, Ferruccio Fazio

Research output: Contribution to journalArticle

153 Citations (Scopus)

Abstract

Cortical regional cerebral perfusion was assessed by N, N, N1-trimethyl-N1-(2)- hydroxy-3-methyl-5-(I-123) iodobenzyl-l, 3-propanediamine 2 HCI 1-123 (HIPDM) and single photon emission computerised tomography (SPECT) in six aphasic and two neglect patients with unilateral subcortical vascular lesions. Assessments were carried out both in the acute phase and after a period ranging from 1 to 6 months after stroke onset. In all patients an almost complete spontaneous recovery occurred and was associated with a significant improvement of cortical perfusion. A relationship between severity of aphasia and degree of cortical hypoperfusion was found, in both the acute and the follow up assessments, in the aphasic subgroup.

Original languageEnglish
Pages (from-to)1269-1276
Number of pages8
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume51
Issue number10
DOIs
Publication statusPublished - 1988

Fingerprint

Aphasia
Perfusion
Stroke
Single-Photon Emission-Computed Tomography
Blood Vessels
N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

Cite this

Recovery from aphasia and neglect after subcortical stroke : neuropsychological and cerebral perfusion study. / Vallar, Giuseppe; Perani, Daniela; Cappa, Stefano F.; Messa, Cristina; Lenzi, Gian Luigi; Fazio, Ferruccio.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 51, No. 10, 1988, p. 1269-1276.

Research output: Contribution to journalArticle

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