Recovery from hepatitis C virus-positive cryoglobulinaemic glomerulonephritis after interferon therapy

C. Mazzaro, A. Faelli, S. Baracetti

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Abstract

The association between mixed cryoglobulinaemia and chronic hepatitis C virus infection has recently been described. Cryoglobulinaemic glomerulonephritis, a complication of mixed cryoglobulinaemia, is usually treated with immunosuppressive therapy, but, given the presence of viral infection, this therapy is no longer recommended. This report concerns a case of a 30-year-old patient with cryoglobulinaemic glomerulonephritis, refractory to steroid treatment, in whom recovery from hepatitis C virus infection was obtained as well as from cryoglobulinaemic glomerulonephritis after interferon therapy. The clinical symptoms and laboratory tests were normal after prolonged interferon therapy and, 3 years after the end of treatment, the patient is free from disease.

Original languageEnglish
Pages (from-to)601-603
Number of pages3
JournalItalian Journal of Gastroenterology and Hepatology
Volume31
Issue number7
Publication statusPublished - 1999

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Keywords

  • Cryoglobulinaemic glomerulonephritis
  • Hepatitis C virus
  • Interferon-alpha
  • Mixed cryoglobulinaemia

ASJC Scopus subject areas

  • Gastroenterology

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