Recurrence of erythema induratum of Bazin in a patient under chemotherapy for breast cancer

Gino A. Vena; Doriana Apruzzi; Michelangelo Vestita; Maria Panaro; Simona Carpagnano; Ruggero Filannino; Nicoletta Cassano

Recurrence of erythema induratum of Bazin in a patient under chemotherapy for breast cancer

Gino A. Vena, Doriana Apruzzi, Michelangelo Vestita, Maria Panaro, Simona Carpagnano, Ruggero Filannino, Nicoletta Cassano

IRCCS Centro di Riferimento Oncologico della Basilicata (CROB)

Research output: Contribution to journal › Article

Abstract

Erythema induratum of Bazin (EIB) is a chronic nodular eruption occurring on the lower legs of young and middle-aged women which is considered the most common tuberculid. A 54-year-old woman, in treatment with chemotherapy for breast cancer, presented subcutaneous erythematous plaques and nodules on the lower limbs. She had been diagnosed with EIB 3 years earlier and diagnostic work-up showed at that time signs suggestive of latent tuberculosis. The suspect of a recurrent form of EIB was confirmed by histopathological examination. A peculiar feature of our report consists in the recurrence of EIB, which is regarded as a hyperergic response against M. tuberculosis antigens, in a patient who was receiving chemotherapy with well-known immunosuppressive effects.

Original language	English
Pages (from-to)	331-333
Number of pages	3
Journal	New Microbiologica
Volume	34
Issue number	3
Publication status	Published - Jul 2011

Keywords

Cancer chemotherapy
Erythema induratum of Bazin
Mycobacterium tuberculosis
Tuberculid
Tuberculosis

ASJC Scopus subject areas

Microbiology (medical)

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Vena, G. A., Apruzzi, D., Vestita, M., Panaro, M., Carpagnano, S., Filannino, R., & Cassano, N. (2011). Recurrence of erythema induratum of Bazin in a patient under chemotherapy for breast cancer. New Microbiologica, 34(3), 331-333.

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abstract = "Erythema induratum of Bazin (EIB) is a chronic nodular eruption occurring on the lower legs of young and middle-aged women which is considered the most common tuberculid. A 54-year-old woman, in treatment with chemotherapy for breast cancer, presented subcutaneous erythematous plaques and nodules on the lower limbs. She had been diagnosed with EIB 3 years earlier and diagnostic work-up showed at that time signs suggestive of latent tuberculosis. The suspect of a recurrent form of EIB was confirmed by histopathological examination. A peculiar feature of our report consists in the recurrence of EIB, which is regarded as a hyperergic response against M. tuberculosis antigens, in a patient who was receiving chemotherapy with well-known immunosuppressive effects.",

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AU - Vena, Gino A.

AU - Apruzzi, Doriana

AU - Vestita, Michelangelo

AU - Panaro, Maria

AU - Carpagnano, Simona

AU - Filannino, Ruggero

AU - Cassano, Nicoletta

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AB - Erythema induratum of Bazin (EIB) is a chronic nodular eruption occurring on the lower legs of young and middle-aged women which is considered the most common tuberculid. A 54-year-old woman, in treatment with chemotherapy for breast cancer, presented subcutaneous erythematous plaques and nodules on the lower limbs. She had been diagnosed with EIB 3 years earlier and diagnostic work-up showed at that time signs suggestive of latent tuberculosis. The suspect of a recurrent form of EIB was confirmed by histopathological examination. A peculiar feature of our report consists in the recurrence of EIB, which is regarded as a hyperergic response against M. tuberculosis antigens, in a patient who was receiving chemotherapy with well-known immunosuppressive effects.

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