Recurrent adenoid cystic carcinoma in the liver: A repeated laparoscopic surgical approach

Vincenzo Scuderi, Antonio Ceriello, Marina Romano, Carla Migliaccio, Giuseppina Marino Marsilia, Fulvio Calise

Research output: Contribution to journalArticlepeer-review


Adenoid cystic carcinoma (ACC) is characterized by a particularly aggressive behavior even many years after resection of primary tumor. The evolution of metastasis dramatically affects the final outcome but resection should always be evaluated. Herein is described a case of aggressive ACC of the parotid gland in a 30-year-old female. She developed local recurrence and lung metastases; then, she also developed two liver metastasis 112 and 132 months after the resection of the primitive cancer of the parotid gland. Both lesions were successfully managed by a laparoscopic approach. Intra-abdominal adhesions after the first surgery were mild, allowing an easier access for the second laparoscopic liver resection. At 1 year follow- up, the patient is liver disease free with a stable lung disease. To our knowledge, this is the first report of a double laparoscopic liver resection for parotid gland's ACC metachronous metastases. Patients with resected ACC need a strict and lifelong follow-up after the resection of the primitive cancer. Also for ACC, a laparoscopic approach to liver metastasis should always be considered as a viable alternative to open surgery. In our experience of over 90 cases, laparoscopic surgery causes less adhesions, allowing an easier approach for repeated resections.

Original languageEnglish
Pages (from-to)301-306
Number of pages6
JournalUpdates in Surgery
Issue number4
Publication statusPublished - 2011


  • Laparoscopic hepatic resection
  • Liver metastases
  • Redo laparoscopic liver resection
  • Salivary adenoid cystic carcinoma

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)


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