Abstract
A 22-year-old female presented, in December 1998, with asthenia, itching and hypereosinophilia. In January 1997, due to the same clinical picture, the patient had inappropriately been diagnosed elsewhere to have an ″idiopathic eosinophilic syndrome″ and complete remission was obtained after short-term steroid treatment. Upon admission, physical examination was negative and blood tests revealed absolute eosinophilia (42%, i.e., 3800 of 9600 white blood cells), aspartate aminotransferase 4 x upper limits of normal, alanine aminotransferase 5 x upper limits of normal and alkaline phosphatase 2 x upper limits of normal. Both liver biopsy and endoscopic retrograde cholangiopancreatography findings were totally consistent with primary sclerosing cholangitis, while all known causes of hypereosinophilia and alteration in liver function tests were carefully excluded. The clinical course was characterized by complete clinical and biochemical normalization in absence of any treatment and further follow-up was completely negative.
| Original language | English |
|---|---|
| Pages (from-to) | 630-633 |
| Number of pages | 4 |
| Journal | Digestive and Liver Disease |
| Volume | 32 |
| Issue number | 7 |
| Publication status | Published - 2000 |
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Keywords
- Cholestasis
- Eosinophilia
- Sclerosing cholangitis
ASJC Scopus subject areas
- Gastroenterology
Cite this
Recurrent cholestasis and hypereosinophilia in a young female. / Pometta, R.; Callea, F.; Mangano, M.; Zuccoli, E.; Conte, D.
In: Digestive and Liver Disease, Vol. 32, No. 7, 2000, p. 630-633.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recurrent cholestasis and hypereosinophilia in a young female
AU - Pometta, R.
AU - Callea, F.
AU - Mangano, M.
AU - Zuccoli, E.
AU - Conte, D.
PY - 2000
Y1 - 2000
N2 - A 22-year-old female presented, in December 1998, with asthenia, itching and hypereosinophilia. In January 1997, due to the same clinical picture, the patient had inappropriately been diagnosed elsewhere to have an ″idiopathic eosinophilic syndrome″ and complete remission was obtained after short-term steroid treatment. Upon admission, physical examination was negative and blood tests revealed absolute eosinophilia (42%, i.e., 3800 of 9600 white blood cells), aspartate aminotransferase 4 x upper limits of normal, alanine aminotransferase 5 x upper limits of normal and alkaline phosphatase 2 x upper limits of normal. Both liver biopsy and endoscopic retrograde cholangiopancreatography findings were totally consistent with primary sclerosing cholangitis, while all known causes of hypereosinophilia and alteration in liver function tests were carefully excluded. The clinical course was characterized by complete clinical and biochemical normalization in absence of any treatment and further follow-up was completely negative.
AB - A 22-year-old female presented, in December 1998, with asthenia, itching and hypereosinophilia. In January 1997, due to the same clinical picture, the patient had inappropriately been diagnosed elsewhere to have an ″idiopathic eosinophilic syndrome″ and complete remission was obtained after short-term steroid treatment. Upon admission, physical examination was negative and blood tests revealed absolute eosinophilia (42%, i.e., 3800 of 9600 white blood cells), aspartate aminotransferase 4 x upper limits of normal, alanine aminotransferase 5 x upper limits of normal and alkaline phosphatase 2 x upper limits of normal. Both liver biopsy and endoscopic retrograde cholangiopancreatography findings were totally consistent with primary sclerosing cholangitis, while all known causes of hypereosinophilia and alteration in liver function tests were carefully excluded. The clinical course was characterized by complete clinical and biochemical normalization in absence of any treatment and further follow-up was completely negative.
KW - Cholestasis
KW - Eosinophilia
KW - Sclerosing cholangitis
UR - http://www.scopus.com/inward/record.url?scp=0033659140&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033659140&partnerID=8YFLogxK
M3 - Article
C2 - 11142565
AN - SCOPUS:0033659140
VL - 32
SP - 630
EP - 633
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
IS - 7
ER -