Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases

A. M. Zina, E. Rampini, E. Fulcheri, S. Bundino, C. Occella, G. Bussolati

Research output: Contribution to journalArticle

Abstract

Two cases of recurrent digital fibromatosis of childhood were studied by electron microscopy and immunohistochemistry, using rabbit anti-actin antisera. The tumor cells were typical myofibroblasts, containing inclusion bodies and bundles of microfilaments. Immunohistochemistry showed the presence of actin in these cells, thus proving the myofibroblastic nature of the tumors. Inclusions were negative or showed a weak annular positivity. A possible explanation of these findings is discussed.

Original languageEnglish
Pages (from-to)22-26
Number of pages5
JournalAmerican Journal of Dermatopathology
Volume8
Issue number1
Publication statusPublished - 1986

Fingerprint

Fibroma
Actins
Immunohistochemistry
Myofibroblasts
Inclusion Bodies
Actin Cytoskeleton
Immune Sera
Neoplasms
Electron Microscopy
Rabbits

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Cite this

Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases. / Zina, A. M.; Rampini, E.; Fulcheri, E.; Bundino, S.; Occella, C.; Bussolati, G.

In: American Journal of Dermatopathology, Vol. 8, No. 1, 1986, p. 22-26.

Research output: Contribution to journalArticle

Zina, A. M. ; Rampini, E. ; Fulcheri, E. ; Bundino, S. ; Occella, C. ; Bussolati, G. / Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases. In: American Journal of Dermatopathology. 1986 ; Vol. 8, No. 1. pp. 22-26.
@article{5884c5889c6a490490ed1aa2013fa7e7,
title = "Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases",
abstract = "Two cases of recurrent digital fibromatosis of childhood were studied by electron microscopy and immunohistochemistry, using rabbit anti-actin antisera. The tumor cells were typical myofibroblasts, containing inclusion bodies and bundles of microfilaments. Immunohistochemistry showed the presence of actin in these cells, thus proving the myofibroblastic nature of the tumors. Inclusions were negative or showed a weak annular positivity. A possible explanation of these findings is discussed.",
author = "Zina, {A. M.} and E. Rampini and E. Fulcheri and S. Bundino and C. Occella and G. Bussolati",
year = "1986",
language = "English",
volume = "8",
pages = "22--26",
journal = "American Journal of Dermatopathology",
issn = "0193-1091",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases

AU - Zina, A. M.

AU - Rampini, E.

AU - Fulcheri, E.

AU - Bundino, S.

AU - Occella, C.

AU - Bussolati, G.

PY - 1986

Y1 - 1986

N2 - Two cases of recurrent digital fibromatosis of childhood were studied by electron microscopy and immunohistochemistry, using rabbit anti-actin antisera. The tumor cells were typical myofibroblasts, containing inclusion bodies and bundles of microfilaments. Immunohistochemistry showed the presence of actin in these cells, thus proving the myofibroblastic nature of the tumors. Inclusions were negative or showed a weak annular positivity. A possible explanation of these findings is discussed.

AB - Two cases of recurrent digital fibromatosis of childhood were studied by electron microscopy and immunohistochemistry, using rabbit anti-actin antisera. The tumor cells were typical myofibroblasts, containing inclusion bodies and bundles of microfilaments. Immunohistochemistry showed the presence of actin in these cells, thus proving the myofibroblastic nature of the tumors. Inclusions were negative or showed a weak annular positivity. A possible explanation of these findings is discussed.

UR - http://www.scopus.com/inward/record.url?scp=0022870659&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022870659&partnerID=8YFLogxK

M3 - Article

C2 - 3706667

AN - SCOPUS:0022870659

VL - 8

SP - 22

EP - 26

JO - American Journal of Dermatopathology

JF - American Journal of Dermatopathology

SN - 0193-1091

IS - 1

ER -