Recurrent Kaposi sarcoma associated with Koebner phenomenon in two HIV-seronegative patients: Two case reports and a review of the literature

Dario Marino, Fiorella Calabrese, Giancarlo Ottaviano, Fabio Biagio La Torre, Mattia Vicario, Mauro Alaibac, Maria Luisa Calabrò

Research output: Contribution to journalArticle

Abstract

RATIONALE: Koebner phenomenon is occasionally reported in patients affected by classic Kaposi sarcoma (KS).

PATIENT CONCERNS: Here, we report 2 cases of KS associated with Koebner phenomenon and the correlation of human herpesvirus 8 molecular analysis with the clinical outcome.

INTERVENTIONS: In the first case, a patient with a history of sporadic cutaneous KS developed a recurrent lesion at the laryngeal tract, the site of a previous nodulectomy. In our second case, immunodeficiency induced by chemotherapy triggered the development of KS and Koebner phenomenon was limited to the skin at the site of safenectomy.

LESSONS: Our observations suggest that careful planning of surgical treatment is required in immunocompetent and immunocompromised patients with a medical history of KS. Moreover, mucosal sites (both respiratory and in the gastrointestinal tract) should be considered as potential sites for KS development.

Original languageEnglish
Pages (from-to)e9467
JournalMedicine
Volume96
Issue number52
DOIs
Publication statusPublished - Dec 2017

Keywords

  • Journal Article

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