Abstract
RATIONALE: Koebner phenomenon is occasionally reported in patients affected by classic Kaposi sarcoma (KS).
PATIENT CONCERNS: Here, we report 2 cases of KS associated with Koebner phenomenon and the correlation of human herpesvirus 8 molecular analysis with the clinical outcome.
INTERVENTIONS: In the first case, a patient with a history of sporadic cutaneous KS developed a recurrent lesion at the laryngeal tract, the site of a previous nodulectomy. In our second case, immunodeficiency induced by chemotherapy triggered the development of KS and Koebner phenomenon was limited to the skin at the site of safenectomy.
LESSONS: Our observations suggest that careful planning of surgical treatment is required in immunocompetent and immunocompromised patients with a medical history of KS. Moreover, mucosal sites (both respiratory and in the gastrointestinal tract) should be considered as potential sites for KS development.
| Original language | English |
|---|---|
| Pages (from-to) | e9467 |
| Journal | Medicine |
| Volume | 96 |
| Issue number | 52 |
| DOIs | |
| Publication status | Published - Dec 2017 |
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Keywords
- Journal Article
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Recurrent Kaposi sarcoma associated with Koebner phenomenon in two HIV-seronegative patients : Two case reports and a review of the literature. / Marino, Dario; Calabrese, Fiorella; Ottaviano, Giancarlo; La Torre, Fabio Biagio; Vicario, Mattia; Alaibac, Mauro; Calabrò, Maria Luisa.
In: Medicine, Vol. 96, No. 52, 12.2017, p. e9467.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recurrent Kaposi sarcoma associated with Koebner phenomenon in two HIV-seronegative patients
T2 - Two case reports and a review of the literature
AU - Marino, Dario
AU - Calabrese, Fiorella
AU - Ottaviano, Giancarlo
AU - La Torre, Fabio Biagio
AU - Vicario, Mattia
AU - Alaibac, Mauro
AU - Calabrò, Maria Luisa
N1 - Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.
PY - 2017/12
Y1 - 2017/12
N2 - RATIONALE: Koebner phenomenon is occasionally reported in patients affected by classic Kaposi sarcoma (KS).PATIENT CONCERNS: Here, we report 2 cases of KS associated with Koebner phenomenon and the correlation of human herpesvirus 8 molecular analysis with the clinical outcome.INTERVENTIONS: In the first case, a patient with a history of sporadic cutaneous KS developed a recurrent lesion at the laryngeal tract, the site of a previous nodulectomy. In our second case, immunodeficiency induced by chemotherapy triggered the development of KS and Koebner phenomenon was limited to the skin at the site of safenectomy.LESSONS: Our observations suggest that careful planning of surgical treatment is required in immunocompetent and immunocompromised patients with a medical history of KS. Moreover, mucosal sites (both respiratory and in the gastrointestinal tract) should be considered as potential sites for KS development.
AB - RATIONALE: Koebner phenomenon is occasionally reported in patients affected by classic Kaposi sarcoma (KS).PATIENT CONCERNS: Here, we report 2 cases of KS associated with Koebner phenomenon and the correlation of human herpesvirus 8 molecular analysis with the clinical outcome.INTERVENTIONS: In the first case, a patient with a history of sporadic cutaneous KS developed a recurrent lesion at the laryngeal tract, the site of a previous nodulectomy. In our second case, immunodeficiency induced by chemotherapy triggered the development of KS and Koebner phenomenon was limited to the skin at the site of safenectomy.LESSONS: Our observations suggest that careful planning of surgical treatment is required in immunocompetent and immunocompromised patients with a medical history of KS. Moreover, mucosal sites (both respiratory and in the gastrointestinal tract) should be considered as potential sites for KS development.
KW - Journal Article
U2 - 10.1097/MD.0000000000009467
DO - 10.1097/MD.0000000000009467
M3 - Article
C2 - 29384936
VL - 96
SP - e9467
JO - Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries
JF - Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries
SN - 0025-7974
IS - 52
ER -