Recurrent laryngeal nerve palsy and substernal goiter. An Italian multicenter study

M. Testini, A. Gurrado, R. Bellantone, P. Brazzarola, R. Cortese, G. De Toma, I. Fabiola Franco, G. Lissidini, C. Pio Lombardi, F. Minerva, G. Di Meo, A. Pasculli, G. Piccinni, L. Rosato

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this retrospective multicenter study was to verify whether the substernal goiter and the type of surgical access could be risk factors for recurrent laryngeal nerve palsy during total thyroidectomy. Between 1999-2008, 14,993 patients underwent total thyroidectomy. Patients were divided into three groups: group A (control; n=14.200, 94.7%), cervical goiters treated through collar incision; group B (n=743, 5.0%) substernal goiters treated by cervical approach; group C (n=50, 0.3%) in which a manubriotomy was performed. Transient and permanent unilateral palsy occurred significantly more frequently in B+C vs. A (P≤.001) and in B vs. A (P≤.001). Transient bilateral palsy was significantly more frequent in B+C vs. A (P≤.043) and in C vs. A (P≤.016). Permanent bilateral palsy was significantly more frequent in B+C vs. A (P≤.041), and in B vs. A (P≤.037). Extension of the goiter into the mediastinum was associated to increased risk of recurrent nerve palsy during total thyroidectomy.

Original languageEnglish
Pages (from-to)183-189
Number of pages7
JournalJournal of visceral surgery
Volume151
Issue number3
DOIs
Publication statusPublished - Jun 1 2014

Keywords

  • Cervico-mediastinal goiter
  • Recurrent laryngeal nerve palsy
  • Substernal goiter
  • Thyroid surgery
  • Total thyroidectomy

ASJC Scopus subject areas

  • Medicine(all)

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