Recurrent proximal white subungual onychomycosis associated with a defect of the polymorphonuclear chemotaxis

Claudia Gianni, Amilcare Cerri, Franco Capsoni, Anna Maria Ongari, Patrizia Rossini, Carlo Crosti

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Proximal white subungual onychomycosis (PWSO) is a rare form of nail infection that occurs almost exclusively in immunocompromised patients. Initially, in several reports, PWSO was described in ARC and AIDS patients. Later this pattern of onychomycosis was observed in patients with renal transplants, who received immunosuppressive therapy, and recently in a woman with active systemic lupus erythematosus (SLE) treated with systemic steroid therapy. We report a case of recurrent PWSO in a woman affected by a defect of polymorphonuclear chemotaxis. The association between PWSO and a defect of neutrophil chemotaxis, not yet described in the literature, suggests a point of discussion about the role of polymorphonuclear leucocyte functions in the defense mechanisms of the host affected by dermatophytosis. In this report the close association between PWSO and an immunocompromised condition is once again described. For this reason the authors emphasize the importance of investigating the common and uncommon causes of immunodeficiency in all patients affected by PWSO.

Original languageEnglish
Pages (from-to)390-392
Number of pages3
JournalEuropean Journal of Dermatology
Volume9
Issue number5
Publication statusPublished - 1999

Fingerprint

Onychomycosis
Chemotaxis
Neutrophils
AIDS-Related Complex
Tinea
Immunocompromised Host
Defense Mechanisms
Immunosuppressive Agents
Nails
Systemic Lupus Erythematosus
Acquired Immunodeficiency Syndrome
Steroids
Transplants
Kidney
Therapeutics
Infection

Keywords

  • Polymorphonuclear chemotaxis
  • Proximal white subungual onychomycosis
  • Trichophyton rubrum

ASJC Scopus subject areas

  • Dermatology

Cite this

Gianni, C., Cerri, A., Capsoni, F., Ongari, A. M., Rossini, P., & Crosti, C. (1999). Recurrent proximal white subungual onychomycosis associated with a defect of the polymorphonuclear chemotaxis. European Journal of Dermatology, 9(5), 390-392.

Recurrent proximal white subungual onychomycosis associated with a defect of the polymorphonuclear chemotaxis. / Gianni, Claudia; Cerri, Amilcare; Capsoni, Franco; Ongari, Anna Maria; Rossini, Patrizia; Crosti, Carlo.

In: European Journal of Dermatology, Vol. 9, No. 5, 1999, p. 390-392.

Research output: Contribution to journalArticle

Gianni, C, Cerri, A, Capsoni, F, Ongari, AM, Rossini, P & Crosti, C 1999, 'Recurrent proximal white subungual onychomycosis associated with a defect of the polymorphonuclear chemotaxis', European Journal of Dermatology, vol. 9, no. 5, pp. 390-392.
Gianni, Claudia ; Cerri, Amilcare ; Capsoni, Franco ; Ongari, Anna Maria ; Rossini, Patrizia ; Crosti, Carlo. / Recurrent proximal white subungual onychomycosis associated with a defect of the polymorphonuclear chemotaxis. In: European Journal of Dermatology. 1999 ; Vol. 9, No. 5. pp. 390-392.
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