Recurrent triploidy of maternal origin

Research output: Contribution to journalArticle

Abstract

Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

Original languageEnglish
Pages (from-to)972-974
Number of pages3
JournalEuropean Journal of Human Genetics
Volume11
Issue number12
DOIs
Publication statusPublished - Dec 2003

Fingerprint

Triploidy
Mothers
Maternal Age
Aneuploidy
Spontaneous Abortion
First Pregnancy Trimester
Chromosome Aberrations
Recurrence
Pregnancy

Keywords

  • Digyny
  • Recurrent abortion
  • Triploidy

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Recurrent triploidy of maternal origin. / Brancati, Francesco; Mingarelli, Rita; Dallapiccola, Bruno.

In: European Journal of Human Genetics, Vol. 11, No. 12, 12.2003, p. 972-974.

Research output: Contribution to journalArticle

@article{a72dfac216794e3c9fbaa3b31a57d691,
title = "Recurrent triploidy of maternal origin",
abstract = "Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.",
keywords = "Digyny, Recurrent abortion, Triploidy",
author = "Francesco Brancati and Rita Mingarelli and Bruno Dallapiccola",
year = "2003",
month = "12",
doi = "10.1038/sj.ejhg.5201076",
language = "English",
volume = "11",
pages = "972--974",
journal = "European Journal of Human Genetics",
issn = "1018-4813",
publisher = "Nature Publishing Group",
number = "12",

}

TY - JOUR

T1 - Recurrent triploidy of maternal origin

AU - Brancati, Francesco

AU - Mingarelli, Rita

AU - Dallapiccola, Bruno

PY - 2003/12

Y1 - 2003/12

N2 - Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

AB - Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

KW - Digyny

KW - Recurrent abortion

KW - Triploidy

UR - http://www.scopus.com/inward/record.url?scp=0346656817&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0346656817&partnerID=8YFLogxK

U2 - 10.1038/sj.ejhg.5201076

DO - 10.1038/sj.ejhg.5201076

M3 - Article

C2 - 14508508

AN - SCOPUS:0346656817

VL - 11

SP - 972

EP - 974

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

SN - 1018-4813

IS - 12

ER -