Recurrent triploidy of maternal origin

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

Original languageEnglish
Pages (from-to)972-974
Number of pages3
JournalEuropean Journal of Human Genetics
Volume11
Issue number12
DOIs
Publication statusPublished - Dec 2003

Fingerprint

Triploidy
Mothers
Maternal Age
Aneuploidy
Spontaneous Abortion
First Pregnancy Trimester
Chromosome Aberrations
Recurrence
Pregnancy

Keywords

  • Digyny
  • Recurrent abortion
  • Triploidy

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Recurrent triploidy of maternal origin. / Brancati, Francesco; Mingarelli, Rita; Dallapiccola, Bruno.

In: European Journal of Human Genetics, Vol. 11, No. 12, 12.2003, p. 972-974.

Research output: Contribution to journalArticle

@article{a72dfac216794e3c9fbaa3b31a57d691,
title = "Recurrent triploidy of maternal origin",
abstract = "Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.",
keywords = "Digyny, Recurrent abortion, Triploidy",
author = "Francesco Brancati and Rita Mingarelli and Bruno Dallapiccola",
year = "2003",
month = "12",
doi = "10.1038/sj.ejhg.5201076",
language = "English",
volume = "11",
pages = "972--974",
journal = "European Journal of Human Genetics",
issn = "1018-4813",
publisher = "Nature Publishing Group",
number = "12",

}

TY - JOUR

T1 - Recurrent triploidy of maternal origin

AU - Brancati, Francesco

AU - Mingarelli, Rita

AU - Dallapiccola, Bruno

PY - 2003/12

Y1 - 2003/12

N2 - Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

AB - Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

KW - Digyny

KW - Recurrent abortion

KW - Triploidy

UR - http://www.scopus.com/inward/record.url?scp=0346656817&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0346656817&partnerID=8YFLogxK

U2 - 10.1038/sj.ejhg.5201076

DO - 10.1038/sj.ejhg.5201076

M3 - Article

VL - 11

SP - 972

EP - 974

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

SN - 1018-4813

IS - 12

ER -