Recurrent triploidy of maternal origin

Francesco Brancati, Rita Mingarelli, Bruno Dallapiccola

Research output: Contribution to journalArticle

Abstract

Triploidy is the most frequent chromosome aberration in first trimester spontaneous abortions. In contrast to aneuploidies due to nondisjunction, increased maternal age is not a risk factor and the mechanism of triploidy remains poorly understood. To date, recurrence of triploidy of maternal origin has been described only in a few families suggesting some underlying genetic factors. Here, we report on a woman who underwent three consecutive triploid pregnancies, in two of which maternal origin of triploidy was proved by molecular analysis.

Original languageEnglish
Pages (from-to)972-974
Number of pages3
JournalEuropean Journal of Human Genetics
Volume11
Issue number12
DOIs
Publication statusPublished - Dec 2003

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Keywords

  • Digyny
  • Recurrent abortion
  • Triploidy

ASJC Scopus subject areas

  • Genetics(clinical)

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