TY - JOUR
T1 - Recurrent venous thromboembolism and abnormal uterine bleeding with anticoagulant and hormone therapy use
AU - Martinelli, Ida
AU - Lensing, Anthonie W A
AU - Middeldorp, Saskia
AU - Levi, Marcel
AU - Beyer-Westendorf, Jan
AU - Bellen, Bonno Van
AU - Bounameaux, Henri
AU - Brighton, Timothy A.
AU - Cohen, Alexander T.
AU - Trajanovic, Mila
AU - Gebel, Martin
AU - Lam, Phuong
AU - Wells, Philip S.
AU - Prins, Martin H.
PY - 2016/3/17
Y1 - 2016/3/17
N2 - Women receiving vitamin K antagonists (VKAs) require adequate contraception because of the potential for fetal complications. It is unknown whether the use of hormonal therapy, especially those containing estrogens, is associated with recurrent venous thromboembolism (VTE) during anticoagulation. Despite the absence of data, World Health Organization guidelines state that use of estrogen-containing contraceptives confers an "unacceptable health risk" during established anticoagulation for VTE. We compared the incidences of recurrent VTE and abnormal uterine bleeding with and without concomitant hormonal therapy in women aged
AB - Women receiving vitamin K antagonists (VKAs) require adequate contraception because of the potential for fetal complications. It is unknown whether the use of hormonal therapy, especially those containing estrogens, is associated with recurrent venous thromboembolism (VTE) during anticoagulation. Despite the absence of data, World Health Organization guidelines state that use of estrogen-containing contraceptives confers an "unacceptable health risk" during established anticoagulation for VTE. We compared the incidences of recurrent VTE and abnormal uterine bleeding with and without concomitant hormonal therapy in women aged
UR - http://www.scopus.com/inward/record.url?scp=84962573834&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84962573834&partnerID=8YFLogxK
U2 - 10.1182/blood-2015-08-665927
DO - 10.1182/blood-2015-08-665927
M3 - Article
AN - SCOPUS:84962573834
VL - 127
SP - 1417
EP - 1425
JO - Blood
JF - Blood
SN - 0006-4971
IS - 11
ER -