Red blood cell lipid alterations in type II diabetes mellitus

Domenico Prisco, Rita Paniccia, Mirella Coppo, Dino Vanni, Pier Giorgio Rogasi, Manuela Tramontana, Rosanna Abbate, Gian Franco Gensini

Research output: Contribution to journalArticle

Abstract

Alterations in blood rheological properties have been reported in diabetes mellitus. Changes in lipid composition of red blood cell (RBC) membranes resulting in an impairement of RBC deformability may play a role in the altered blood rheological pattern. The aim of this study was to investigate the lipid composition of RBC membrane in a group of patients affected by type II diabetes (age 21-45 years), selected on the basis of the absence of complications and good metabolic control, and in a group of suitable control subjects. Saturated fatty acid amounts in the different phospholipid fractions were significantly higher in diabetics than in controls (p

Original languageEnglish
Pages (from-to)751-758
Number of pages8
JournalThrombosis Research
Volume54
Issue number6
DOIs
Publication statusPublished - Jun 15 1989

Keywords

  • cholesterol
  • diabetes mellitus
  • fatty acids
  • phospholipids
  • red blood cells

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Hematology

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    Prisco, D., Paniccia, R., Coppo, M., Vanni, D., Rogasi, P. G., Tramontana, M., Abbate, R., & Gensini, G. F. (1989). Red blood cell lipid alterations in type II diabetes mellitus. Thrombosis Research, 54(6), 751-758. https://doi.org/10.1016/0049-3848(89)90139-4