Red blood cell plasma Li ratio variability in affective patients

M. Catalano; M. Gasperini; A. Lucca; V. Brancato; Enrico Smeraldi

doi:10.1159/000118385

Red blood cell plasma Li ratio variability in affective patients

M. Catalano, M. Gasperini, A. Lucca, V. Brancato, Enrico Smeraldi

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

In the light of the existence of controversial reports on the stability of Li ratio, we investigated a group of affective patients wishing to verify intraindividual stability of this parameter in the different phases of the disease, that is normothymia and manic and depressive episodes. We found lower Li ratios for the periods preceding any relapse. Further, we analyzed whether or not some epidemiological factors, such as polarity, sex, actual age, age of onset, might affect interindividual variability of the Li ratio. We found that they did not as single factors. Interaction between polarity and the presence of relapses appeared to significantly affect the Li ratio.

Original language	English
Pages (from-to)	5-8
Number of pages	4
Journal	Neuropsychobiology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1159/000118385
Publication status	Published - 1987

Keywords

Affective disorders
Li ratio
Variability

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry
Neuropsychology and Physiological Psychology
Neuroscience(all)
Psychology(all)

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10.1159/000118385

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AU - Gasperini, M.

AU - Lucca, A.

AU - Brancato, V.

AU - Smeraldi, Enrico

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N2 - In the light of the existence of controversial reports on the stability of Li ratio, we investigated a group of affective patients wishing to verify intraindividual stability of this parameter in the different phases of the disease, that is normothymia and manic and depressive episodes. We found lower Li ratios for the periods preceding any relapse. Further, we analyzed whether or not some epidemiological factors, such as polarity, sex, actual age, age of onset, might affect interindividual variability of the Li ratio. We found that they did not as single factors. Interaction between polarity and the presence of relapses appeared to significantly affect the Li ratio.

AB - In the light of the existence of controversial reports on the stability of Li ratio, we investigated a group of affective patients wishing to verify intraindividual stability of this parameter in the different phases of the disease, that is normothymia and manic and depressive episodes. We found lower Li ratios for the periods preceding any relapse. Further, we analyzed whether or not some epidemiological factors, such as polarity, sex, actual age, age of onset, might affect interindividual variability of the Li ratio. We found that they did not as single factors. Interaction between polarity and the presence of relapses appeared to significantly affect the Li ratio.

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KW - Li ratio

KW - Variability

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Red blood cell plasma Li ratio variability in affective patients

Abstract

Keywords

ASJC Scopus subject areas

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