Red blood cell plasma Li ratio variability in affective patients

M. Catalano, M. Gasperini, A. Lucca, V. Brancato, Enrico Smeraldi

Research output: Contribution to journalArticlepeer-review


In the light of the existence of controversial reports on the stability of Li ratio, we investigated a group of affective patients wishing to verify intraindividual stability of this parameter in the different phases of the disease, that is normothymia and manic and depressive episodes. We found lower Li ratios for the periods preceding any relapse. Further, we analyzed whether or not some epidemiological factors, such as polarity, sex, actual age, age of onset, might affect interindividual variability of the Li ratio. We found that they did not as single factors. Interaction between polarity and the presence of relapses appeared to significantly affect the Li ratio.

Original languageEnglish
Pages (from-to)5-8
Number of pages4
Issue number1
Publication statusPublished - 1987


  • Affective disorders
  • Li ratio
  • Variability

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychology(all)


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