Abstract
Evaluation of: Man MA, Nicolau D. Surgical treatment to increase the success rate of multidrug-resistant tuberculosis. Eur. J. Cardiothorac. Surg. 42, e9-e12 (2012). The global emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB represents a core challenge for global tuberculosis control. MDR-TB and extensively drug-resistant TB are more difficult to treat and have a worse outcome compared with drug-susceptible disease. Surgery has proved to improve treatment success in MDR-TB patients. This study was designed to assess the impact of surgery in a cohort of MDR-TB patients. The authors evaluate one of the largest cohorts treated by a single center, demonstrating that specialized thoracic surgery centers may achieve excellent results with a low rate of complications after surgery, and proposing an effective model of teamwork based on pulmonologists and surgeons. A review of the evidence supporting the role of surgery in addition to chemotherapy to improve treatment outcomes in difficult-to-treat cases of TB is also performed.
| Original language | English |
|---|---|
| Pages (from-to) | 1109-1115 |
| Number of pages | 7 |
| Journal | Expert Review of Anti-Infective Therapy |
| Volume | 10 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2012 |
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Keywords
- extensively drug-resistant tuberculosis
- multidrug-resistant tuberculosis
- surgical treatment
- thoracotomy
ASJC Scopus subject areas
- Infectious Diseases
- Microbiology (medical)
- Microbiology
- Virology
Cite this
Rediscovering high technology from the past : Thoracic surgery is back on track for multidrug-resistant tuberculosis. / Pontali, Emanuele; Matteelli, Alberto; D'Ambrosio, Lia; Centis, Rosella; Migliori, Giovanni Battista.
In: Expert Review of Anti-Infective Therapy, Vol. 10, No. 10, 10.2012, p. 1109-1115.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Rediscovering high technology from the past
T2 - Thoracic surgery is back on track for multidrug-resistant tuberculosis
AU - Pontali, Emanuele
AU - Matteelli, Alberto
AU - D'Ambrosio, Lia
AU - Centis, Rosella
AU - Migliori, Giovanni Battista
PY - 2012/10
Y1 - 2012/10
N2 - Evaluation of: Man MA, Nicolau D. Surgical treatment to increase the success rate of multidrug-resistant tuberculosis. Eur. J. Cardiothorac. Surg. 42, e9-e12 (2012). The global emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB represents a core challenge for global tuberculosis control. MDR-TB and extensively drug-resistant TB are more difficult to treat and have a worse outcome compared with drug-susceptible disease. Surgery has proved to improve treatment success in MDR-TB patients. This study was designed to assess the impact of surgery in a cohort of MDR-TB patients. The authors evaluate one of the largest cohorts treated by a single center, demonstrating that specialized thoracic surgery centers may achieve excellent results with a low rate of complications after surgery, and proposing an effective model of teamwork based on pulmonologists and surgeons. A review of the evidence supporting the role of surgery in addition to chemotherapy to improve treatment outcomes in difficult-to-treat cases of TB is also performed.
AB - Evaluation of: Man MA, Nicolau D. Surgical treatment to increase the success rate of multidrug-resistant tuberculosis. Eur. J. Cardiothorac. Surg. 42, e9-e12 (2012). The global emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB represents a core challenge for global tuberculosis control. MDR-TB and extensively drug-resistant TB are more difficult to treat and have a worse outcome compared with drug-susceptible disease. Surgery has proved to improve treatment success in MDR-TB patients. This study was designed to assess the impact of surgery in a cohort of MDR-TB patients. The authors evaluate one of the largest cohorts treated by a single center, demonstrating that specialized thoracic surgery centers may achieve excellent results with a low rate of complications after surgery, and proposing an effective model of teamwork based on pulmonologists and surgeons. A review of the evidence supporting the role of surgery in addition to chemotherapy to improve treatment outcomes in difficult-to-treat cases of TB is also performed.
KW - extensively drug-resistant tuberculosis
KW - multidrug-resistant tuberculosis
KW - surgical treatment
KW - thoracotomy
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U2 - 10.1586/eri.12.108
DO - 10.1586/eri.12.108
M3 - Article
C2 - 23199397
AN - SCOPUS:84870621238
VL - 10
SP - 1109
EP - 1115
JO - Expert Review of Anti-Infective Therapy
JF - Expert Review of Anti-Infective Therapy
SN - 1478-7210
IS - 10
ER -