Rediscovering high technology from the past: Thoracic surgery is back on track for multidrug-resistant tuberculosis

Emanuele Pontali; Alberto Matteelli; Lia D'Ambrosio; Rosella Centis; Giovanni Battista Migliori

doi:10.1586/eri.12.108

Rediscovering high technology from the past: Thoracic surgery is back on track for multidrug-resistant tuberculosis

Emanuele Pontali, Alberto Matteelli, Lia D'Ambrosio, Rosella Centis, Giovanni Battista Migliori

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Article › peer-review

Abstract

Evaluation of: Man MA, Nicolau D. Surgical treatment to increase the success rate of multidrug-resistant tuberculosis. Eur. J. Cardiothorac. Surg. 42, e9-e12 (2012). The global emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB represents a core challenge for global tuberculosis control. MDR-TB and extensively drug-resistant TB are more difficult to treat and have a worse outcome compared with drug-susceptible disease. Surgery has proved to improve treatment success in MDR-TB patients. This study was designed to assess the impact of surgery in a cohort of MDR-TB patients. The authors evaluate one of the largest cohorts treated by a single center, demonstrating that specialized thoracic surgery centers may achieve excellent results with a low rate of complications after surgery, and proposing an effective model of teamwork based on pulmonologists and surgeons. A review of the evidence supporting the role of surgery in addition to chemotherapy to improve treatment outcomes in difficult-to-treat cases of TB is also performed.

Original language	English
Pages (from-to)	1109-1115
Number of pages	7
Journal	Expert Review of Anti-Infective Therapy
Volume	10
Issue number	10
DOIs	https://doi.org/10.1586/eri.12.108
Publication status	Published - Oct 2012

Keywords

extensively drug-resistant tuberculosis
multidrug-resistant tuberculosis
surgical treatment
thoracotomy

ASJC Scopus subject areas

Infectious Diseases
Microbiology (medical)
Microbiology
Virology

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Rediscovering high technology from the past : Thoracic surgery is back on track for multidrug-resistant tuberculosis. / Pontali, Emanuele; Matteelli, Alberto; D'Ambrosio, Lia; Centis, Rosella ; Migliori, Giovanni Battista.

In: Expert Review of Anti-Infective Therapy, Vol. 10, No. 10, 10.2012, p. 1109-1115.

Research output: Contribution to journal › Article › peer-review

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