Reduced left ventricular mechanical efficiency in elderly patients with coronary artery disease

Carlo Vigorito, A. Giordano, P. Ferraro, P. Supino, L. De Caprio, B. Giordano, F. Lionetti, M. De Pasquale, F. Rengo

Research output: Contribution to journalArticle

Abstract

We evaluated left ventricular (LV) mechanical efficiency in 23 elderly patients (mean age 67± 2) with coronary artery disease (CAD) and in 22 patients younger than 65 years (mean age 49± 8) with similar severity of CAD (2.4± 0.8 and 2.2± 0.8 vessels per patient, respectively) and history of myocardial infarction (34% and 41%, respectively). LV mechanical efficiency was calculated as the ratio of LV work per minute and myocardial O2 consumption. LV stroke volume was calculated from left ventriculography. Coronary blood flow was measured by thermodilution. Older patients had lower values of LV stroke volume (49± 16 vs 73± 16 mL, p2 consumption was similar in the two groups, LV mechanical efficiency was lower in older CAD patients (16.2± 15 vs 23.8± 12%, p

Original languageEnglish
Pages (from-to)205-209
Number of pages5
JournalAging clinical and experimental research
Volume7
Issue number4
DOIs
Publication statusPublished - 1995

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Keywords

  • Coronary artery disease
  • elderly
  • LV efficiency

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

Vigorito, C., Giordano, A., Ferraro, P., Supino, P., De Caprio, L., Giordano, B., Lionetti, F., De Pasquale, M., & Rengo, F. (1995). Reduced left ventricular mechanical efficiency in elderly patients with coronary artery disease. Aging clinical and experimental research, 7(4), 205-209. https://doi.org/10.1007/BF03324336