Reduced natural killer cell activity in major depression: neuroendocrine implications

Dina Nerozzi, Angela Santoni, Giuseppe Bersani, Armando Magnani, Annamaria Bressan, Augusto Pasini, Italo Antonozzi, Gaetano Frajese

Research output: Contribution to journalArticlepeer-review


Natural killer cell activity (NKCA) was significantly reduced in a group of depressed patients, melancholic subtype, compared to sex- and age-matched controls. Corticotropin and cortisol values were significantly higher in the depressed subjects than in the controls, but no correlation between high hormone levels and low immunological activity was found in the patients.

Original languageEnglish
Pages (from-to)295-301
Number of pages7
Issue number4
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Endocrine and Autonomic Systems
  • Psychology(all)


Dive into the research topics of 'Reduced natural killer cell activity in major depression: neuroendocrine implications'. Together they form a unique fingerprint.

Cite this