Reduced regional systolic function evolved compacted segments in noncompaction

Giovanni Fazio, Giuseppina Novo, Luciana D'angelo, Monica Lunetta, Loredana Sutera, Gabriele Di Gesaro, Giuseppe Indovina, Filippo Ferrara, Salvatore Novo

Research output: Contribution to journalArticlepeer-review


In a recent report about noncompaction Nemes et al. reported that systolic left ventricular (LV) dysfunction assessed using the wall motion score during 2D echocardiography in noncompaction is not confined to noncompacted LV segments. These results confirmed some published reports of our group. Recently we analyzed a population of 238 patients affected by noncompaction, and demonstrated that the number of noncompacted segment is uncorrelated with the degree of systolic dysfunction. It is an attractive hypothesis that the systolic dysfunction could be depend on the fibrosis of the left ventricle, itself a consequence of microcirculatory dysfunction, which has been confirmed by reports that describe microvascular dysfunction using myocardial scintigraphy.

Original languageEnglish
Pages (from-to)442
Number of pages1
JournalInternational Journal of Cardiology
Issue number3
Publication statusPublished - Apr 30 2010


  • Delay enhancement
  • Noncompaction
  • Scintigraphy
  • Segmental alterations
  • Systolic dysfunction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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