Reduced taste perception in Al amyloidosis. A frequently unnoticed sensory impairment

M. G. Marinone, M. G. Marinone, G. Merlini

Research output: Contribution to journalArticle

Abstract

Background. Sporadic observations suggest a possible taste impairment in AL amyloidosis, but the frequency and intensity of this sensory anomaly are not known. Materials and Methods. We submitted 21 AL amyloidotic patients, drawn from subjects referred to the Amyloidosis Study Center of the Department of Internal Medicine and Medical Therapy, University of Pavia, to suprathreshold scaling analysis. Results. Taste acuity was reduced in most of them. Every taste showed independent behavior, and 90% of these patients were hypogeusic. True ageusia for one or two tastes was observed in 35% of patients. No patient was aware of reduced taste acuity. Macroglossia did not seem to play a prominent role in dulling tastes. Conclusions. Impairment of taste perception suggests that gustative neuropathy is a frequently unnoticed expression of sensory involvement in AL amyloidosis.

Original languageEnglish
Pages (from-to)110-115
Number of pages6
JournalHaematologica
Volume81
Issue number2
Publication statusPublished - 1996

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Taste Perception
Amyloidosis
Ageusia
Macroglossia
Internal Medicine

Keywords

  • AL amyloidosis
  • Gustalive neuropathy
  • Taste acuity

ASJC Scopus subject areas

  • Hematology

Cite this

Reduced taste perception in Al amyloidosis. A frequently unnoticed sensory impairment. / Marinone, M. G.; Marinone, M. G.; Merlini, G.

In: Haematologica, Vol. 81, No. 2, 1996, p. 110-115.

Research output: Contribution to journalArticle

Marinone, M. G. ; Marinone, M. G. ; Merlini, G. / Reduced taste perception in Al amyloidosis. A frequently unnoticed sensory impairment. In: Haematologica. 1996 ; Vol. 81, No. 2. pp. 110-115.
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