Abstract
Three major determinants of lung injury associated with mechanical ventilation have been clearly identified: high pressure/high volume, the shear forces caused by intratidal collapse and decollapse leading to barotrauma/volotrauma/biotrauma. The lung protective strategy aims to reduce the impact of all three determinants. A groundbreaking study showed that reduced tidal volume is less dangerous than high tidal volume, but the researchers did not apply "full" lung protective strategy and did not take into account the shear forces. "Full" protective lung strategy was tested in only one study and in a limited number of patients. Several physiologic studies strongly suggest the advantages of the lung protective strategy.
| Original language | English |
|---|---|
| Pages (from-to) | 45-50 |
| Number of pages | 6 |
| Journal | Current Opinion in Critical Care |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2002 |
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ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
Cite this
Reduced tidal volumes and lung protective ventilatory strategies : Where do we go from here? / Gattinoni, Luciano; Chiumello, Davide; Russo, Riccarda.
In: Current Opinion in Critical Care, Vol. 8, No. 1, 2002, p. 45-50.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reduced tidal volumes and lung protective ventilatory strategies
T2 - Where do we go from here?
AU - Gattinoni, Luciano
AU - Chiumello, Davide
AU - Russo, Riccarda
PY - 2002
Y1 - 2002
N2 - Three major determinants of lung injury associated with mechanical ventilation have been clearly identified: high pressure/high volume, the shear forces caused by intratidal collapse and decollapse leading to barotrauma/volotrauma/biotrauma. The lung protective strategy aims to reduce the impact of all three determinants. A groundbreaking study showed that reduced tidal volume is less dangerous than high tidal volume, but the researchers did not apply "full" lung protective strategy and did not take into account the shear forces. "Full" protective lung strategy was tested in only one study and in a limited number of patients. Several physiologic studies strongly suggest the advantages of the lung protective strategy.
AB - Three major determinants of lung injury associated with mechanical ventilation have been clearly identified: high pressure/high volume, the shear forces caused by intratidal collapse and decollapse leading to barotrauma/volotrauma/biotrauma. The lung protective strategy aims to reduce the impact of all three determinants. A groundbreaking study showed that reduced tidal volume is less dangerous than high tidal volume, but the researchers did not apply "full" lung protective strategy and did not take into account the shear forces. "Full" protective lung strategy was tested in only one study and in a limited number of patients. Several physiologic studies strongly suggest the advantages of the lung protective strategy.
UR - http://www.scopus.com/inward/record.url?scp=0036178429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036178429&partnerID=8YFLogxK
U2 - 10.1097/00075198-200202000-00008
DO - 10.1097/00075198-200202000-00008
M3 - Article
C2 - 12205406
AN - SCOPUS:0036178429
VL - 8
SP - 45
EP - 50
JO - Current Opinion in Critical Care
JF - Current Opinion in Critical Care
SN - 1070-5295
IS - 1
ER -