Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia

G. Remuzzi, D. Marchesi, C. Zoja, D. Muratore, G. Mecca, R. Misiani, E. Rossi, M. Barbato, P. Capetta, M. B. Donati, G. de Gaetano

Research output: Contribution to journalArticle

163 Citations (Scopus)

Abstract

Prostacyclin production was significantly depressed in foetal and placental vascular tissues from five patients with severe pre-eclampsia in comparison to vascular tissues from women with uncomplicated pregnancy. Such an abnormality may be responsible for a reduced blood flow and defective fetal nutrition thus playing a major role in the pathogenesis of this syndrome.

Original languageEnglish
Pages (from-to)105-110
Number of pages6
JournalProstaglandins
Volume20
Issue number1
DOIs
Publication statusPublished - 1980

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Umbilicus
Epoprostenol
Pre-Eclampsia
Blood Vessels
Tissue
Nutrition
Blood
Pregnancy

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia. / Remuzzi, G.; Marchesi, D.; Zoja, C.; Muratore, D.; Mecca, G.; Misiani, R.; Rossi, E.; Barbato, M.; Capetta, P.; Donati, M. B.; de Gaetano, G.

In: Prostaglandins, Vol. 20, No. 1, 1980, p. 105-110.

Research output: Contribution to journalArticle

Remuzzi, G, Marchesi, D, Zoja, C, Muratore, D, Mecca, G, Misiani, R, Rossi, E, Barbato, M, Capetta, P, Donati, MB & de Gaetano, G 1980, 'Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia', Prostaglandins, vol. 20, no. 1, pp. 105-110. https://doi.org/10.1016/0090-6980(80)90010-6
Remuzzi, G. ; Marchesi, D. ; Zoja, C. ; Muratore, D. ; Mecca, G. ; Misiani, R. ; Rossi, E. ; Barbato, M. ; Capetta, P. ; Donati, M. B. ; de Gaetano, G. / Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia. In: Prostaglandins. 1980 ; Vol. 20, No. 1. pp. 105-110.
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