Reduction in deep vein thrombosis incidence in intensive care after a clinician education program

M. Boddi, F. Barbani, R. Abbate, M. Bonizzoli, S. Batacchi, E. Lucente, M. Chiostri, G. F. Gensini, A. Peris

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Deep vein thrombosis (DVT) is a major complication in intensive care units (ICU) but dedicated guidelines on its management are still lacking. Objectives and Methods: This study investigated the effect of a 1-year educational program for the implementation of DVT prophylaxis on the incidence of inferior limb DVT in a mixed-bed ICU that admits high-risk surgical and trauma patients, investigated during a first retrospective phase [126 patients, SAPS II score 42 (28-54)] and a following prospective phase [264 patients, SAPS II score II 41 (27-55)]. The role of baseline and time-dependent DVT risk factors in DVT occurrence was also investigated during the prospective phase. Results: The educational program on implementation of DVT prophylaxis was associated with a significant decrease in DVT incidence from 11.9% to 4.5% (P <0.01) and in the mean length of ICU stay (P <0.01). Combined with pharmacological prophylaxis, the use of elastic compressive stockings significantly also increased in the prospective phase (P <0.01). The duration of mechanical ventilation, vasopressor administration and neuromuscular block were significantly different between DVT-positive and DVT-negative patients (P <0.01). Multivariate analysis identified neuromuscular block as the strongest independent predictor for DVT incidence. Conclusion: One-year ICU-based educational programs on implementation of DVT prophylaxis were associated with a significant decrease in the incidence of DVT and also in the length of stay in ICU.

Original languageEnglish
Pages (from-to)121-128
Number of pages8
JournalJournal of Thrombosis and Haemostasis
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 2010

Keywords

  • Deep vein thrombosis
  • DVT prophylaxis
  • Intensive care unit
  • Thrombosis risk factor
  • Trauma
  • Ultrasound surveillance

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Reduction in deep vein thrombosis incidence in intensive care after a clinician education program'. Together they form a unique fingerprint.

Cite this