Reduction of mitral valve regurgitation caused by acute papillary muscle ischemia

Marco Magnoni, Stefano Coli, Giovanni La Canna, Carlo Meloni, Domenico Cianflone, Attilio Maseri

Research output: Contribution to journalArticlepeer-review


Background: A 67-year-old man was admitted to a coronary care unit for non-ST-segment elevation myocardial infarction with complicating acute heart failure. Severe mitral regurgitation was detected by echocardiography at presentation. Repeat echocardiography carried out during another ischemic episode revealed a marked reduction in the patient's mitral regurgitation that was related to decreased apical traction of the valve leaflets. Investigations: Physical examination, electrocardiography, laboratory tests, coronary angiography, chest radiography, echocardiography. Diagnosis: Mitral regurgitation associated with acute coronary syndrome. Management: Early revascularization by percutaneous coronary intervention, supported by pharmacological therapy to decrease left ventricular filling pressure.

Original languageEnglish
Pages (from-to)51-54
Number of pages4
JournalNature Clinical Practice Cardiovascular Medicine
Issue number1
Publication statusPublished - Jan 2007

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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