Reed-Sternberg cell leukaemia

P. Cavalli, M. Cazzola, P. G. Gobbi, M. Gorini, A. Malfitano, A. Riccardi, E. Ascari

Research output: Contribution to journalArticlepeer-review


A case of Reed-Sternberg (R-S) leukaemia is described, and the results of the morphological, cytochemical and cytokinetic studies on the circulating neoplastic cells are reported. Detailed data are given for each of the 3 types of abnormal circulating cells; abnormal mononuclear (AM) cells. Hodgkin's (H) cells and R-S cells. Our results cannot discriminate whether R-S cells derive from monocyte-macrophages or from B-cell lineage. However, some data suggest that H and R-S cells may likely originate from AM cells. The unfavourable clinical significance of the appearance of circulating R-S cells is discussed taking into account the other few cases reported in literature.

Original languageEnglish
Pages (from-to)63-70
Number of pages8
Issue number1
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Cancer Research


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