Reference Values for Right Ventricular Volumes and Ejection Fraction With Real-Time Three-Dimensional Echocardiography: Evaluation in a Large Series of Normal Subjects

Gloria Tamborini, Nina Ajmone Marsan, Paola Gripari, Francesco Maffessanti, Denise Brusoni, Manuela Muratori, Enrico G. Caiani, Cesare Fiorentini, Mauro Pepi

Research output: Contribution to journalArticle

Abstract

Background: The quantification of right ventricular (RV) size and function is of diagnostic and prognostic importance. Recently, new software for the analysis of RV geometry using three-dimensional (3D) echocardiographic images has been validated. The aim of this study was to provide normal reference values for RV volumes and function using this technique. Methods: A total of 245 subjects, including 15 to 20 subjects for each gender and age decile, were studied. Dedicated 3D acquisitions of the right ventricle were obtained in all subjects. Results: The mean RV end-diastolic and end-systolic volumes were 49 ± 10 and 16 ± 6 mL/m2 respectively, and the mean RV ejection fraction was 67 ± 8%. Significant correlations were observed between RV parameters and body surface area. Normalized RV volumes were significantly correlated with age and gender. RV ejection fractions were lower in men, but differences across age deciles were not evident. Conclusion: The current study provides normal reference values for RV volumes and function that may be useful for the identification of clinical abnormalities.

Original languageEnglish
Pages (from-to)109-115
Number of pages7
JournalJournal of the American Society of Echocardiography
Volume23
Issue number2
DOIs
Publication statusPublished - Feb 2010

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Three-Dimensional Echocardiography
Right Ventricular Function
Stroke Volume
Reference Values
Body Surface Area
Heart Ventricles
Software

Keywords

  • Normal reference values
  • Right ventricle
  • Three-dimensional echocardiography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Reference Values for Right Ventricular Volumes and Ejection Fraction With Real-Time Three-Dimensional Echocardiography: Evaluation in a Large Series of Normal Subjects",
abstract = "Background: The quantification of right ventricular (RV) size and function is of diagnostic and prognostic importance. Recently, new software for the analysis of RV geometry using three-dimensional (3D) echocardiographic images has been validated. The aim of this study was to provide normal reference values for RV volumes and function using this technique. Methods: A total of 245 subjects, including 15 to 20 subjects for each gender and age decile, were studied. Dedicated 3D acquisitions of the right ventricle were obtained in all subjects. Results: The mean RV end-diastolic and end-systolic volumes were 49 ± 10 and 16 ± 6 mL/m2 respectively, and the mean RV ejection fraction was 67 ± 8{\%}. Significant correlations were observed between RV parameters and body surface area. Normalized RV volumes were significantly correlated with age and gender. RV ejection fractions were lower in men, but differences across age deciles were not evident. Conclusion: The current study provides normal reference values for RV volumes and function that may be useful for the identification of clinical abnormalities.",
keywords = "Normal reference values, Right ventricle, Three-dimensional echocardiography",
author = "Gloria Tamborini and Marsan, {Nina Ajmone} and Paola Gripari and Francesco Maffessanti and Denise Brusoni and Manuela Muratori and Caiani, {Enrico G.} and Cesare Fiorentini and Mauro Pepi",
year = "2010",
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AU - Tamborini, Gloria

AU - Marsan, Nina Ajmone

AU - Gripari, Paola

AU - Maffessanti, Francesco

AU - Brusoni, Denise

AU - Muratori, Manuela

AU - Caiani, Enrico G.

AU - Fiorentini, Cesare

AU - Pepi, Mauro

PY - 2010/2

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N2 - Background: The quantification of right ventricular (RV) size and function is of diagnostic and prognostic importance. Recently, new software for the analysis of RV geometry using three-dimensional (3D) echocardiographic images has been validated. The aim of this study was to provide normal reference values for RV volumes and function using this technique. Methods: A total of 245 subjects, including 15 to 20 subjects for each gender and age decile, were studied. Dedicated 3D acquisitions of the right ventricle were obtained in all subjects. Results: The mean RV end-diastolic and end-systolic volumes were 49 ± 10 and 16 ± 6 mL/m2 respectively, and the mean RV ejection fraction was 67 ± 8%. Significant correlations were observed between RV parameters and body surface area. Normalized RV volumes were significantly correlated with age and gender. RV ejection fractions were lower in men, but differences across age deciles were not evident. Conclusion: The current study provides normal reference values for RV volumes and function that may be useful for the identification of clinical abnormalities.

AB - Background: The quantification of right ventricular (RV) size and function is of diagnostic and prognostic importance. Recently, new software for the analysis of RV geometry using three-dimensional (3D) echocardiographic images has been validated. The aim of this study was to provide normal reference values for RV volumes and function using this technique. Methods: A total of 245 subjects, including 15 to 20 subjects for each gender and age decile, were studied. Dedicated 3D acquisitions of the right ventricle were obtained in all subjects. Results: The mean RV end-diastolic and end-systolic volumes were 49 ± 10 and 16 ± 6 mL/m2 respectively, and the mean RV ejection fraction was 67 ± 8%. Significant correlations were observed between RV parameters and body surface area. Normalized RV volumes were significantly correlated with age and gender. RV ejection fractions were lower in men, but differences across age deciles were not evident. Conclusion: The current study provides normal reference values for RV volumes and function that may be useful for the identification of clinical abnormalities.

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