Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions

A systematic review

Cristian Navarrete-Dechent, Antonio P. DeRosa, Caterina Longo, Konstantinos Liopyris, Margaret Oliviero, Harold Rabinovitz, Ashfaq A. Marghoob, Allan C. Halpern, Giovanni Pellacani, Alon Scope, Manu Jain

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.

Original languageEnglish
JournalJournal of the American Academy of Dermatology
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Seborrheic Keratosis
Lentigo
Keratosis
Terminology
Confocal Microscopy
Lichens
Basal Cell Carcinoma
Squamous Cell Carcinoma
Skin
Dermis
Epidermis
Meta-Analysis
Research Personnel
Guidelines
Research

Keywords

  • actinic keratosis
  • basal cell carcinoma
  • diagnosis
  • lichen planus-like keratosis
  • melanoma
  • nonmelanoma skin cancer
  • reflectance confocal microscopy
  • seborrheic keratosis
  • squamous cell carcinoma

ASJC Scopus subject areas

  • Dermatology

Cite this

Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions : A systematic review. / Navarrete-Dechent, Cristian; DeRosa, Antonio P.; Longo, Caterina; Liopyris, Konstantinos; Oliviero, Margaret; Rabinovitz, Harold; Marghoob, Ashfaq A.; Halpern, Allan C.; Pellacani, Giovanni; Scope, Alon; Jain, Manu.

In: Journal of the American Academy of Dermatology, 01.01.2019.

Research output: Contribution to journalReview article

Navarrete-Dechent, C, DeRosa, AP, Longo, C, Liopyris, K, Oliviero, M, Rabinovitz, H, Marghoob, AA, Halpern, AC, Pellacani, G, Scope, A & Jain, M 2019, 'Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions: A systematic review', Journal of the American Academy of Dermatology. https://doi.org/10.1016/j.jaad.2018.12.007
Navarrete-Dechent, Cristian ; DeRosa, Antonio P. ; Longo, Caterina ; Liopyris, Konstantinos ; Oliviero, Margaret ; Rabinovitz, Harold ; Marghoob, Ashfaq A. ; Halpern, Allan C. ; Pellacani, Giovanni ; Scope, Alon ; Jain, Manu. / Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions : A systematic review. In: Journal of the American Academy of Dermatology. 2019.
@article{3ed9372477b24af2bf1f7fb34c544860,
title = "Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions: A systematic review",
abstract = "Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5{\%} reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7{\%}) versus 78 (74.2{\%}) for BCC; 60 (64.5{\%}) versus 33 (34.5{\%}) for SCC, and 15 (45.4{\%}) versus 18 (54.5{\%}) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.",
keywords = "actinic keratosis, basal cell carcinoma, diagnosis, lichen planus-like keratosis, melanoma, nonmelanoma skin cancer, reflectance confocal microscopy, seborrheic keratosis, squamous cell carcinoma",
author = "Cristian Navarrete-Dechent and DeRosa, {Antonio P.} and Caterina Longo and Konstantinos Liopyris and Margaret Oliviero and Harold Rabinovitz and Marghoob, {Ashfaq A.} and Halpern, {Allan C.} and Giovanni Pellacani and Alon Scope and Manu Jain",
year = "2019",
month = "1",
day = "1",
doi = "10.1016/j.jaad.2018.12.007",
language = "English",
journal = "Journal of the American Academy of Dermatology",
issn = "0190-9622",
publisher = "Mosby Inc.",

}

TY - JOUR

T1 - Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions

T2 - A systematic review

AU - Navarrete-Dechent, Cristian

AU - DeRosa, Antonio P.

AU - Longo, Caterina

AU - Liopyris, Konstantinos

AU - Oliviero, Margaret

AU - Rabinovitz, Harold

AU - Marghoob, Ashfaq A.

AU - Halpern, Allan C.

AU - Pellacani, Giovanni

AU - Scope, Alon

AU - Jain, Manu

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.

AB - Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.

KW - actinic keratosis

KW - basal cell carcinoma

KW - diagnosis

KW - lichen planus-like keratosis

KW - melanoma

KW - nonmelanoma skin cancer

KW - reflectance confocal microscopy

KW - seborrheic keratosis

KW - squamous cell carcinoma

UR - http://www.scopus.com/inward/record.url?scp=85063092068&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063092068&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2018.12.007

DO - 10.1016/j.jaad.2018.12.007

M3 - Review article

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

ER -