Reflex responses of sympathetic preganglionic neurones initiated by different cardiovascular receptors in spinal animals

Massimo Pagani, Peter J. Schwartz, Robert Banks, Federico Lombardi, Alberto Malliani

Research output: Contribution to journalArticle

Abstract

We recorded the discharge of 66 single sympathetic preganglionic fibres isolated from the third and fourth left thoracic sympathetic rami communicantes of spinal vagotomized cats. Various mechanical and chemical stimuli were applied to different cardiovascular receptors in order to initiate reflex responses. Stimuli affecting mainly cardiac receptors always increased the discharge of the responsive fibres. Conversely, stimuli affecting simultaneously cardiac and vascular receptors or restricted to aortic receptors, either increased or decreased the discharge of the same fibres. The responses, consistent for each individual fibre, were reflex in nature. The data demonstrate that both specificity and convergence regulate cardiovascular sympathetic spinal reflexes.

Original languageEnglish
Pages (from-to)215-225
Number of pages11
JournalBrain Research
Volume68
Issue number2
DOIs
Publication statusPublished - Mar 22 1974

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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