Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype

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Abstract

BACKGROUND AND PURPOSE: Progressive brain atrophy is a well-known feature of multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS phenotypes. METHODS: Dual-echo and T1-weighted MR images were obtained in 70 patients with MS and 10 healthy control subjects at entry and after 15 months. Within-group changes in regional atrophy were assessed by applying Structural Image Evaluation Using Normalization of Atrophy software and statistical parametric mapping analysis. Reported differences are for P

Original languageEnglish
Pages (from-to)341-346
Number of pages6
JournalAmerican Journal of Neuroradiology
Volume26
Issue number2
Publication statusPublished - 2005

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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