Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype

Elisabetta Pagani; Maria A. Rocca; Antonio Gallo; Marco Rovaris; Vittorio Martinelli; Giancarlo Comi; Massimo Filippi

Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype

Elisabetta Pagani, Maria A. Rocca, Antonio Gallo, Marco Rovaris, Vittorio Martinelli, Giancarlo Comi, Massimo Filippi

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND AND PURPOSE: Progressive brain atrophy is a well-known feature of multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS phenotypes. METHODS: Dual-echo and T1-weighted MR images were obtained in 70 patients with MS and 10 healthy control subjects at entry and after 15 months. Within-group changes in regional atrophy were assessed by applying Structural Image Evaluation Using Normalization of Atrophy software and statistical parametric mapping analysis. Reported differences are for P

Original language	English
Pages (from-to)	341-346
Number of pages	6
Journal	American Journal of Neuroradiology
Volume	26
Issue number	2
Publication status	Published - 2005

ASJC Scopus subject areas

Clinical Neurology
Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

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Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype. / Pagani, Elisabetta; Rocca, Maria A.; Gallo, Antonio; Rovaris, Marco ; Martinelli, Vittorio ; Comi, Giancarlo ; Filippi, Massimo.

In: American Journal of Neuroradiology, Vol. 26, No. 2, 2005, p. 341-346.

Research output: Contribution to journal › Article › peer-review

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AU - Pagani, Elisabetta

AU - Rocca, Maria A.

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AU - Rovaris, Marco

AU - Martinelli, Vittorio

AU - Comi, Giancarlo

AU - Filippi, Massimo

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AB - BACKGROUND AND PURPOSE: Progressive brain atrophy is a well-known feature of multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS phenotypes. METHODS: Dual-echo and T1-weighted MR images were obtained in 70 patients with MS and 10 healthy control subjects at entry and after 15 months. Within-group changes in regional atrophy were assessed by applying Structural Image Evaluation Using Normalization of Atrophy software and statistical parametric mapping analysis. Reported differences are for P

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Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype

Abstract

ASJC Scopus subject areas

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