Regional cerebral blood flow and anxiety: A correlation study in neurologically normal patients

G. Rodriguez, P. Cogorno, A. Gris, S. Marenco, C. Mesiti, F. Nobili, G. Rosadini

Research output: Contribution to journalArticlepeer-review


Regional CBF (rCBF) was evaluated by the 133Xe inhalation method in 60 neurologically normal patients (30 men and 30 women) and hemispheric and regional values were correlated with anxiety measurements collected by a self-rating questionnaire before and after the examination. Statistically significant negative correlations between rCBF and anxiety measures were found. rCBF reduction for high anxiety levels is in line with results previously reported by others and could be related to lower performance levels for moderately high anxiety scores as those reported in the present population. This could perhaps be explained by rearrangement of flow from cortical zones to deeper areas of the brain, classically known to be implicated in the control of emotions. However, these results should be interpreted cautiously, since they were obtained in patients and not in normal subjects.

Original languageEnglish
Pages (from-to)410-416
Number of pages7
JournalJournal of Cerebral Blood Flow and Metabolism
Issue number3
Publication statusPublished - Jan 1 1989

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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