Regional diastolic function by tissue Doppler echocardiography in systemic sclerosis: Correlation with clinical variables

Edoardo Rosato, Stefania Maione, Antonio Vitarelli, Anna Giunta, Luca Fontanella, Laura Tanturri De Horatio, Francesco Cacciatore, Michele Proietti, Simonetta Pisarri, Felice Salsano

Research output: Contribution to journalArticlepeer-review

Abstract

The incidence of left ventricular (LV) diastolic dysfunction is increased in systemic sclerosis (SSc), while systolic dysfunction is present in a small percentage of patients. The aim of this study was to asses the LV "regional" diastolic abnormalities in SSc patients by the mean of Doppler tissue imaging (DTI). Echocardiographic echo-Doppler (DE) and DTI parameters were analyzed for 67 SSc patients: abnormal E/A ratio at DE was detected in 24, while abnormal e/a at DTI was observed in 41. A significant prevalence of DTI diastolic abnormalities in the segments reflecting longitudinal versus those reflecting radial LV motion was found. The segments of the basal regions of LV myocardium were significantly more involved than those of the middle portion. Linear correlation was observed between the extent of the diastolic abnormalities and the duration of disease. Longitudinal myocardial systolic velocities were significantly reduced in patients with abnormal e/a DTI.

Original languageEnglish
Pages (from-to)913-919
Number of pages7
JournalRheumatology International
Volume29
Issue number8
DOIs
Publication statusPublished - Jun 2009

Keywords

  • Doppler tissue imaging
  • Regional left ventricular systolic and diastolic function
  • Systemic sclerosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Fingerprint Dive into the research topics of 'Regional diastolic function by tissue Doppler echocardiography in systemic sclerosis: Correlation with clinical variables'. Together they form a unique fingerprint.

Cite this