Regional eruptive neurofibromas

Roberto Betti, Amilcare Cerr, Lorenzo Gualandri, Laura Moneghini, Carlo Crosti

Research output: Contribution to journalArticlepeer-review


A 71-year-old woman presented with multiple, flesh-colored, papular lesions on the left dorsal side of the hand which had erupted 5 years earlier. No café-au-lait spots, freckles, or Lisch nodules were detected. Family history did not disclose neurofibromas or abnormal pigmentation. Two biopsy specimens of the lesions showed circumscribed, non-encapsulated neurofibromas. Segmental neurofibromatosis is characterized by the unilateral, segmental appearance of neurofibromas and/or café-au-lait spots in the absence of genetic transmission. The authors discuss the significance of localized multiple cutaneous neurofibromas in the absence of family history and suggest the possibility of a cutaneous hamartoma.

Original languageEnglish
Pages (from-to)198-201
Number of pages4
JournalJournal of Dermatology
Issue number3
Publication statusPublished - 1997


  • café-au-lait spots
  • localized hamartomas
  • neurofibromas
  • regional eruptive lesions
  • segmental neurofibromatosis

ASJC Scopus subject areas

  • Dermatology


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