Abstract
Myocardial perfusion measurements were obtained with positron emission tomography under basal conditions and after intravenous dipyridamole infusion (0.56 mg/kg over 4 minutes) to determine if myocardial perfusion is maximized in areas of resting wall motion abnormalities in patients with stable angina. Thirty-three patients with no history of myocardial infarction, and with coronary stenosis >50% involving the left anterior descending (n = 24) and left circumflex (n = 9) coronary arteries were evaluated. Quantitative perfusion images were recorded twice in each subject using nitrogen-13 ammonia at baseline and after intravenous administration of dipyridamole. Computer-assisted analysis of left ventriculograms showed abnormal wall motion in the stenosis-related regions in 16 patients (group 1), and normal regional function in 17 (group 2). The flow values in the anterior and posterolateral wall were considered to reflect left anterior and left circumflex coronary artery flow, respectively. Quantitative angiography showed that coronary stenosis severity was higher in group 1 than in group 2 (cross-sectional area reduction 94 ± 7% vs 87 ± 11%; p
| Original language | English |
|---|---|
| Pages (from-to) | 990-994 |
| Number of pages | 5 |
| Journal | The American Journal of Cardiology |
| Volume | 72 |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - Nov 1 1993 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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Regional myocardial blood flow in stable angina pectoris associated with isolated significant narrowing of either the left anterior descending or left circumflex coronary artery. / Sambuceti, Gianmario; Parodi, Oberdan; Marzullo, Paolo; Giorgetti, Assuero; Fusani, Lucio; Puccini, Giacomo; Salvadori, Piero; L'Abbate, Antonio.
In: The American Journal of Cardiology, Vol. 72, No. 14, 01.11.1993, p. 990-994.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Regional myocardial blood flow in stable angina pectoris associated with isolated significant narrowing of either the left anterior descending or left circumflex coronary artery
AU - Sambuceti, Gianmario
AU - Parodi, Oberdan
AU - Marzullo, Paolo
AU - Giorgetti, Assuero
AU - Fusani, Lucio
AU - Puccini, Giacomo
AU - Salvadori, Piero
AU - L'Abbate, Antonio
PY - 1993/11/1
Y1 - 1993/11/1
N2 - Myocardial perfusion measurements were obtained with positron emission tomography under basal conditions and after intravenous dipyridamole infusion (0.56 mg/kg over 4 minutes) to determine if myocardial perfusion is maximized in areas of resting wall motion abnormalities in patients with stable angina. Thirty-three patients with no history of myocardial infarction, and with coronary stenosis >50% involving the left anterior descending (n = 24) and left circumflex (n = 9) coronary arteries were evaluated. Quantitative perfusion images were recorded twice in each subject using nitrogen-13 ammonia at baseline and after intravenous administration of dipyridamole. Computer-assisted analysis of left ventriculograms showed abnormal wall motion in the stenosis-related regions in 16 patients (group 1), and normal regional function in 17 (group 2). The flow values in the anterior and posterolateral wall were considered to reflect left anterior and left circumflex coronary artery flow, respectively. Quantitative angiography showed that coronary stenosis severity was higher in group 1 than in group 2 (cross-sectional area reduction 94 ± 7% vs 87 ± 11%; p
AB - Myocardial perfusion measurements were obtained with positron emission tomography under basal conditions and after intravenous dipyridamole infusion (0.56 mg/kg over 4 minutes) to determine if myocardial perfusion is maximized in areas of resting wall motion abnormalities in patients with stable angina. Thirty-three patients with no history of myocardial infarction, and with coronary stenosis >50% involving the left anterior descending (n = 24) and left circumflex (n = 9) coronary arteries were evaluated. Quantitative perfusion images were recorded twice in each subject using nitrogen-13 ammonia at baseline and after intravenous administration of dipyridamole. Computer-assisted analysis of left ventriculograms showed abnormal wall motion in the stenosis-related regions in 16 patients (group 1), and normal regional function in 17 (group 2). The flow values in the anterior and posterolateral wall were considered to reflect left anterior and left circumflex coronary artery flow, respectively. Quantitative angiography showed that coronary stenosis severity was higher in group 1 than in group 2 (cross-sectional area reduction 94 ± 7% vs 87 ± 11%; p
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UR - http://www.scopus.com/inward/citedby.url?scp=0027485385&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(93)90850-C
DO - 10.1016/0002-9149(93)90850-C
M3 - Article
C2 - 8213599
AN - SCOPUS:0027485385
VL - 72
SP - 990
EP - 994
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 14
ER -