Regional myocardial blood flow redistribution as a cause of postprandial angina pectoris

Ragavendra R. Baliga; Stuart D. Rosen; Paolo G. Camici; Jaspal S. Kooner

Regional myocardial blood flow redistribution as a cause of postprandial angina pectoris

Ragavendra R. Baliga, Stuart D. Rosen, Paolo G. Camici, Jaspal S. Kooner

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Background - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with ¹⁵O-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects. The standard liquid meal precipitated angina pectoris in all patients. Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97±0.14 to 1.14±0.25 ml · min^-1 · g^-1, P-1 · g^-1, P-1 · g^- ¹, P-1 · g^-1, P

Original language	English
Pages (from-to)	1144-1149
Number of pages	6
Journal	Circulation
Volume	97
Issue number	12
Publication status	Published - Mar 31 1998

Keywords

Angina
Blood flow
Coronary disease
Food

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

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title = "Regional myocardial blood flow redistribution as a cause of postprandial angina pectoris",

abstract = "Background - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with 15O-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects. The standard liquid meal precipitated angina pectoris in all patients. Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97±0.14 to 1.14±0.25 ml · min-1 · g-1, P-1 · g-1, P-1 · g- 1, P-1 · g-1, P",

keywords = "Angina, Blood flow, Coronary disease, Food",

author = "Baliga, {Ragavendra R.} and Rosen, {Stuart D.} and Camici, {Paolo G.} and Kooner, {Jaspal S.}",

year = "1998",

month = mar,

day = "31",

language = "English",

volume = "97",

pages = "1144--1149",

journal = "Circulation",

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publisher = "Lippincott Williams and Wilkins",

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T1 - Regional myocardial blood flow redistribution as a cause of postprandial angina pectoris

AU - Baliga, Ragavendra R.

AU - Rosen, Stuart D.

AU - Camici, Paolo G.

AU - Kooner, Jaspal S.

PY - 1998/3/31

Y1 - 1998/3/31

N2 - Background - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with 15O-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects. The standard liquid meal precipitated angina pectoris in all patients. Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97±0.14 to 1.14±0.25 ml · min-1 · g-1, P-1 · g-1, P-1 · g- 1, P-1 · g-1, P

AB - Background - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with 15O-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects. The standard liquid meal precipitated angina pectoris in all patients. Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97±0.14 to 1.14±0.25 ml · min-1 · g-1, P-1 · g-1, P-1 · g- 1, P-1 · g-1, P

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KW - Coronary disease

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