Abstract
Background - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with 15O-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects. The standard liquid meal precipitated angina pectoris in all patients. Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97±0.14 to 1.14±0.25 ml · min-1 · g-1, P-1 · g-1, P-1 · g- 1, P-1 · g-1, P
Original language | English |
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Pages (from-to) | 1144-1149 |
Number of pages | 6 |
Journal | Circulation |
Volume | 97 |
Issue number | 12 |
Publication status | Published - Mar 31 1998 |
Keywords
- Angina
- Blood flow
- Coronary disease
- Food
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine