Regional myocardial blood flow redistribution as a cause of postprandial angina pectoris

Ragavendra R. Baliga, Stuart D. Rosen, Paolo G. Camici, Jaspal S. Kooner

Research output: Contribution to journalArticlepeer-review

Abstract

Background - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with 15O-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects. The standard liquid meal precipitated angina pectoris in all patients. Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97±0.14 to 1.14±0.25 ml · min-1 · g-1, P-1 · g-1, P-1 · g- 1, P-1 · g-1, P

Original languageEnglish
Pages (from-to)1144-1149
Number of pages6
JournalCirculation
Volume97
Issue number12
Publication statusPublished - Mar 31 1998

Keywords

  • Angina
  • Blood flow
  • Coronary disease
  • Food

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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