Regional thrombolytic therapy and stent implantation in an acutely occluded aortobifemoral bypass graft

Angelo Anzuini, Roberto Chiesa, Flavio Airoldi, Giorgio Gimelli, Efrem Civilini, Laura Dordoni, Silla Frigerio, Marcelo R L Moura, Yochai Birnbaun, Antonio Colombo, Alberto Margonato, Carlo Briguori

Research output: Contribution to journalArticlepeer-review


Purpose: To present a case highlighting the efficacy of local thrombolysis followed by stent implantation in acute occlusion of an aortobifemoral bypass graft. Case Report: A 47-year-old man was referred to our catheterization laboratory for acute bilateral limb ischemia occurring 18 hours after an aortobifemoral bypass procedure. Angiography documented total occlusion due to massive thrombosis of the grafts. After 24 hours of local thrombolysis, repeat angiography showed complete lysis of the thrombus and an intimal flap in the abdominal aorta. A Palmaz stent was successfully implanted to cover the flap and restore adequate flow. At 1 year, the patient remains asymptomatic, and angiography showed patency of both the stent and the grafts. Conclusions: Based on this patient's response, local thrombolysis followed by stenting may be a safe and effective alternative to reoperation for the treatment of acute graft thrombosis caused by an intimal aortic flap. More experience with this approach is necessary to determine if this is an acceptable and effective mode of treatment.

Original languageEnglish
Pages (from-to)86-89
Number of pages4
JournalJournal of Endovascular Therapy
Issue number1
Publication statusPublished - Feb 2003


  • Aortobifemoral graft
  • Graft failure
  • Graft thrombosis
  • Intimal flap
  • Palmaz stent
  • Recombinant tissue plasminogen activator
  • Thrombolysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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