Regression rate of clinical HPV infection of the lower genital tract during pregnancy after laser CO2 surgery

A. Frega, E. Baiocco, S. Pace, A. Palazzo, R. Iacovelli, A. Biamonti, M. Moscarini, P. Stentella

Research output: Contribution to journalArticlepeer-review


The objective of the study was to evaluate the effects of laser CO 2 surgery during pregnancy to prevent clinical HPV infection recurrence after delivery and vertical infection. A case-control study was performed on 280 pregnant women affected by clinical HPV infection treated during pregnancy with 256 women treated three months after delivery. Follow-up was performed for a minimum of three colposcopic examinations for two years. Recurrence rates were calculated considering the number of positive findings for at least one colposcopic examination confirmed by biopsy after a negative control in a year. Statistical comparison of rates was performed by χ2 and Fisher's exact test. Recurrence rates were higher in the women treated in postpartum (p <.01) than in the group treated during gestation (p <.005). Clinical HPV infections treated during the second trimester of pregnancy showed a sensitive decrease in recurrence rate of infection. Rarity of respiratory papillomatosis makes conclusions inconsistent for the prevention of vertical infection.

Original languageEnglish
Pages (from-to)93-95
Number of pages3
JournalClinical and Experimental Obstetrics and Gynecology
Issue number2
Publication statusPublished - 2006


  • HPV
  • Laser CO
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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