MECCANISMI DI REGOLAZIONE DELLA SECREZIONE DI PROLATTINA. POSSIBILE RUOLO DEL SISTEMA RENINA-ANGIOTENSINA IPOFISARIO

Translated title of the contribution: Regulation factors in prolactin secretion. Possible role of the pituitary renin-angiotensin system

C. Lombardi, C. Missale, M. Poli, R. De Cotiis, M. Memo, C. Spedini, P. F. Spano

Research output: Contribution to journalArticlepeer-review

Abstract

Recent studies have shown a possible role of different factors in the regulation of prolactin secretion. In fact many neurotransmitters (dopamine) and peptides can modulate prolactin release from anterior pituitary lactotrophs. In vitro and in vivo studies, Angiotensin II has been shown to increase prolactin release. On the basis of these data we have studied the effects of enalapril (ACE-Inhibitor) on baseline plasma prolactin in nine hypertensive post-menopausal women. The results indicate that 15-day inhibition of angiotensin-converting enzyme by enalapril significantly reduced serum prolactin levels. These data suggest that the Angiotensin II may play a role in the control of prolactin secretion in hypertensive women.

Translated title of the contributionRegulation factors in prolactin secretion. Possible role of the pituitary renin-angiotensin system
Original languageItalian
Pages (from-to)587-590
Number of pages4
JournalMinerva Medica
Volume81
Issue number9
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Medicine(all)

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