Regulation of the macrophage content of neoplasms by chemoattractants

B. Bottazzi, N. Polentarutti, R. Acero, A. Balsari, D. Boraschi, P. Ghezzi, M. Salmona, A. Mantovani

Research output: Contribution to journalArticle

Abstract

Factor chemotactic for mononuclear phagocytes was found in supernatant fluids of cultured human and mouse tumor cells. In 11 mouse tumors there was a correlation observed between chemotactic activity and macrophage content of neoplastic tissues. Tumor-derived chemoattractants appear to participate in the regulation of tumor-associated macrophages.

Original languageEnglish
Pages (from-to)210-212
Number of pages3
JournalScience
Volume220
Issue number4593
DOIs
Publication statusPublished - 1983

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ASJC Scopus subject areas

  • General

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