Regulatory assessment of chemicals within OECD member countries, EU and in Russia

Natalja Fjodorova, Marjana Novich, Marjan Vrachko, Nina Kharchevnikova, Zoya Zholdakova, Oxana Sinitsyna, Emilio Benfenati

Research output: Contribution to journalArticle

Abstract

The chemical risk assessment is essesntial part of new chemical legislation registration, evaluation, and authorization of chemicals (REACH). The article presents a review of chemical legislation policies in the European Union (EU) and in Russia, and changes in chemicals regulations to meet the requirement of REACH. The risk assessment paradigm, toxicological parameters, safe limits and classification criteria used by different agencies and authorities in different countries are reported. Our investigation also focuses on comparison of chemical risk assessment criteria used in OECD member countries and in Russia. Tendencies in harmonization in accordance with the globally harmonized system of classification and labeling of chemicals (GHS) are discussed.

Original languageEnglish
Pages (from-to)40-88
Number of pages49
JournalJournal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews
Volume26
Issue number1
DOIs
Publication statusPublished - Jan 2008

Keywords

  • Chemical risk assessment
  • Chemicals policy
  • Evaluation and authorization of chemicals (REACH)
  • Exposure guidelines
  • Exposure standards
  • Globally harmonized system of classification and labeling of chemicals (GHS)
  • Hazardous
  • Registration
  • Regulations
  • Risk

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Oncology
  • Cancer Research
  • Toxicology
  • Health, Toxicology and Mutagenesis

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