Rehabilitation in neuro-oncology: A meta-analysis of published data and a mono-institutional experience

Vincenzo Formica, Girolamo Del Monte, Ilaria Giacchetti, Italia Grenga, Salvatore Giaquinto, Massimo Fini, Mario Roselli

Research output: Contribution to journalArticlepeer-review


Background. Rehabilitation for cancer patients with central nervous system (CNS) involvement is rarely considered and data on its use are limited. The purpose of the present study is to collect all available published data on neuro-oncology rehabilitation and perform a meta-analysis where results were presented in a comparable manner. Moreover, the authors report results on cancer patients with neurological disabilities undergoing rehabilitation at their unit. Study design. A PubMed search was performed to identify studies regarding cancer patients with CNS involvement undergoing inpatient physical rehabilitation. Studies with a complete functional evaluation at admission and discharge were selected. As the most common evaluation scales were Functional Independence Measure (FIM) and Barthel Index (BI), only articles with complete FIM and/or BI data were selected for the meta-analysis. Moreover, 23 cancer patients suffering from diverse neurological disabilities underwent standard rehabilitation program between April 2005 and December 2007 at the San Raffaele Pisana Rehabilitation Center. Patient demographics and relevant clinical data were collected. Motricity Index, Trunk Control Test score, and BI were monitored during rehabilitation to assess patient progresses. BI results of patients in this study were included in the meta-analysis. Results. The meta-analysis included results of a total of 994 patients. A statistically significant (P

Original languageEnglish
Pages (from-to)119-126
Number of pages8
JournalIntegrative Cancer Therapies
Issue number2
Publication statusPublished - Jun 2011


  • Barthel Index
  • Functional Independence Motricity scale
  • meta-analysis
  • neuro-oncology rehabilitation

ASJC Scopus subject areas

  • Complementary and alternative medicine
  • Oncology


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