Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature

Palma Maurizi, Michele Antonio Capozza, Silvia Triarico, Maria Luisa Perrotta, Vito Briganti, Antonio Ruggiero

Research output: Contribution to journalReview articlepeer-review

Abstract

BACKGROUND: Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age.

CASE PRESENTATION: We describe the case of a 9-year-old boy with a diagnosis of PUNLMP, who underwent to cystoscopic lesion removal and later to endoscopic lesion removal and intra-bladder Mitomycin-c (MMC) instillations for relapsed disease. Follow-up investigations at five years showed disease negativity.

CONCLUSIONS: Intra-bladder MMC instillation may allow obtaining the complete remission with bladder-sparing for paediatric patients with a high-risk relapsed PUNLMP.

Original languageEnglish
Pages (from-to)36
JournalBMC Urology
Volume19
Issue number1
DOIs
Publication statusPublished - May 9 2019

Keywords

  • Child
  • Cystectomy/methods
  • Humans
  • Male
  • Neoplasm Recurrence, Local/diagnostic imaging
  • Urinary Bladder Neoplasms/diagnostic imaging
  • Urothelium/diagnostic imaging

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