Relapsing neoplastic seeding after percutaneous ethanol injection for hepatocellular carcinoma. Clinical and ultrasonographic findings in a cirrhotic patient

Giampiero Francica, Gianpiero Marone, Valentina D'Angelo, Giuseppe Iodice, Pietro Pastore, Maria Elisa Albo, Gabriella Altamura, Antonio De Falco, Luigi Sauchelli

Research output: Contribution to journalArticlepeer-review

Abstract

A case of neoplastic implant after percutaneous ethanol injection (PEI) therapy for hepatocellular carcinoma (HCC) occurring in two steps is described. A 74-year-old male cirrhotic patient underwent PEI for a 5-cm HCC nodule. To obtain complete tumoral necrosis, 80 ml were injected under sonographic guidance in four sessions. Ten months after the completion of PEI a subcutaneous nodule was palpated in the abdominal wall within the area of needle punctures. Histologic examination of the excised nodule confirmed the sonographic and Power Doppler diagnosis of metastatic HCC. At the US exam scheduled three months later a non-palpable subcutaneous nodule of 16 mm was appreciated near the surgical wound. Once again metastatic HCC was demonstrated at pathological examination.

Original languageEnglish
Pages (from-to)185-189
Number of pages5
JournalEuropean Journal of Ultrasound
Volume6
Issue number3
DOIs
Publication statusPublished - Dec 1997

Keywords

  • Hepatocellular carcinoma
  • Needle track seeding
  • Percutaneous ethanol injection
  • Ultrasound

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Bioengineering
  • Radiology Nuclear Medicine and imaging
  • Acoustics and Ultrasonics

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