Studio dei rapporti tra arousal e crisi epilettiche focali in sonno: Valutazione tramite analisi del CAP

Translated title of the contribution: Relation between arousal and focal epileptic seizure during sleep: Evaluation by CAP analysis

R. Manni, M. Terzaghi, C. A. Galimberti, C. Arbasino, V. Rustioni, D. Marchese

Research output: Contribution to journalArticlepeer-review

Abstract

The Cyclic Alternating Pattern (CAP) is a physiological oscillatory activity consisting of repetitive sequences of activation phase (A) and inhibitory phase (B) during NREM sleep, expressing a state of sleep instability (arousal), which was documented to modulate most of the paroxysmal epileptic events during sleep. Macro- and microstructure (CAP) of sleep was analized in 14 laboratory or ambulatory Polysomnographic (PSG) recordings of 12 adult patients affected by symptomatic or cryptogenic localization-related epilepsy. Forty-four out of the 56 seizures recorded (78%) occurred during a CAP sequence, in close relation to A (namely A2) phase. Fifty-five per cent of the seizures was followed by awakening; 62% of the seizures occurring during non-CAP sleep was followed by CAP. The A phase of CAP appears to be a trigger for most of the seizures recorded independently of the macrostructural stage of NREM sleep. In turn the seizure occurrence results in sleep fragmentation.

Translated title of the contributionRelation between arousal and focal epileptic seizure during sleep: Evaluation by CAP analysis
Original languageItalian
Pages (from-to)365-367
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number121-122
Publication statusPublished - Jul 2003

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Relation between arousal and focal epileptic seizure during sleep: Evaluation by CAP analysis'. Together they form a unique fingerprint.

Cite this