Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium

Carlotta Galeone; Federica Turati; Zuo Feng Zhang; Valentina Guercio; Alessandra Tavani; Diego Serraino; Paul Brennan; Eleonora Fabianova; Jola Lissowska; Dana Mates; Peter Rudnai; Oxana Shangina; Neonila Szeszenia-Dabrowska; Thomas L. Vaughan; Karl Kelsey; Michael Mcclean; Fabio Levi; Richard B. Hayes; Mark P. Purdue; Cristina Bosetti; Hermann Brenner; Claudio Pelucchi; Yuan Chin Amy Lee; Mia Hashibe; Paolo Boffetta; Carlo La Vecchia

doi:10.1002/mnfr.201500042

Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium

Carlotta Galeone, Federica Turati, Zuo Feng Zhang, Valentina Guercio, Alessandra Tavani, Diego Serraino, Paul Brennan, Eleonora Fabianova, Jola Lissowska, Dana Mates, Peter Rudnai, Oxana Shangina, Neonila Szeszenia-Dabrowska, Thomas L. Vaughan, Karl Kelsey, Michael Mcclean, Fabio Levi, Richard B. Hayes, Mark P. Purdue, Cristina BosettiHermann Brenner, Claudio Pelucchi, Yuan Chin Amy Lee, Mia Hashibe, Paolo Boffetta, Carlo La Vecchia

Research output: Contribution to journal › Article › peer-review

Abstract

Scope: Only a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Methods and results: We analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to

Original language	English
Pages (from-to)	1641-1650
Number of pages	10
Journal	Molecular Nutrition and Food Research
Volume	59
Issue number	9
DOIs	https://doi.org/10.1002/mnfr.201500042
Publication status	Published - Sep 1 2015

Keywords

Allium vegetables
Diet
Garlic
Head and Neck Neoplasms
Onion

ASJC Scopus subject areas

Food Science
Biotechnology

Access to Document

10.1002/mnfr.201500042

Cite this

Galeone, C., Turati, F., Zhang, Z. F., Guercio, V., Tavani, A., Serraino, D., Brennan, P., Fabianova, E., Lissowska, J., Mates, D., Rudnai, P., Shangina, O., Szeszenia-Dabrowska, N., Vaughan, T. L., Kelsey, K., Mcclean, M., Levi, F., Hayes, R. B., Purdue, M. P., ... La Vecchia, C. (2015). Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium. Molecular Nutrition and Food Research, 59(9), 1641-1650. https://doi.org/10.1002/mnfr.201500042

Galeone, C, Turati, F, Zhang, ZF, Guercio, V, Tavani, A, Serraino, D, Brennan, P, Fabianova, E, Lissowska, J, Mates, D, Rudnai, P, Shangina, O, Szeszenia-Dabrowska, N, Vaughan, TL, Kelsey, K, Mcclean, M, Levi, F, Hayes, RB, Purdue, MP, Bosetti, C, Brenner, H, Pelucchi, C, Lee, YCA, Hashibe, M, Boffetta, P & La Vecchia, C 2015, 'Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium', Molecular Nutrition and Food Research, vol. 59, no. 9, pp. 1641-1650. https://doi.org/10.1002/mnfr.201500042

@article{de24a88576b34125921c41bc9af62d74,

title = "Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium",

abstract = "Scope: Only a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Methods and results: We analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to ",

keywords = "Allium vegetables, Diet, Garlic, Head and Neck Neoplasms, Onion",

author = "Carlotta Galeone and Federica Turati and Zhang, {Zuo Feng} and Valentina Guercio and Alessandra Tavani and Diego Serraino and Paul Brennan and Eleonora Fabianova and Jola Lissowska and Dana Mates and Peter Rudnai and Oxana Shangina and Neonila Szeszenia-Dabrowska and Vaughan, {Thomas L.} and Karl Kelsey and Michael Mcclean and Fabio Levi and Hayes, {Richard B.} and Purdue, {Mark P.} and Cristina Bosetti and Hermann Brenner and Claudio Pelucchi and Lee, {Yuan Chin Amy} and Mia Hashibe and Paolo Boffetta and {La Vecchia}, Carlo",

year = "2015",

month = sep,

day = "1",

doi = "10.1002/mnfr.201500042",

language = "English",

volume = "59",

pages = "1641--1650",

journal = "Molecular Nutrition and Food Research",

issn = "1613-4125",

publisher = "Wiley-VCH Verlag",

number = "9",

}

TY - JOUR

T1 - Relation of allium vegetables intake with head and neck cancers

T2 - Evidence from the INHANCE consortium

AU - Galeone, Carlotta

AU - Turati, Federica

AU - Zhang, Zuo Feng

AU - Guercio, Valentina

AU - Tavani, Alessandra

AU - Serraino, Diego

AU - Brennan, Paul

AU - Fabianova, Eleonora

AU - Lissowska, Jola

AU - Mates, Dana

AU - Rudnai, Peter

AU - Shangina, Oxana

AU - Szeszenia-Dabrowska, Neonila

AU - Vaughan, Thomas L.

AU - Kelsey, Karl

AU - Mcclean, Michael

AU - Levi, Fabio

AU - Hayes, Richard B.

AU - Purdue, Mark P.

AU - Bosetti, Cristina

AU - Brenner, Hermann

AU - Pelucchi, Claudio

AU - Lee, Yuan Chin Amy

AU - Hashibe, Mia

AU - Boffetta, Paolo

AU - La Vecchia, Carlo

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Scope: Only a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Methods and results: We analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to

AB - Scope: Only a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Methods and results: We analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to

KW - Allium vegetables

KW - Diet

KW - Garlic

KW - Head and Neck Neoplasms

KW - Onion

UR - http://www.scopus.com/inward/record.url?scp=84942835034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942835034&partnerID=8YFLogxK

U2 - 10.1002/mnfr.201500042

DO - 10.1002/mnfr.201500042

M3 - Article

AN - SCOPUS:84942835034

VL - 59

SP - 1641

EP - 1650

JO - Molecular Nutrition and Food Research

JF - Molecular Nutrition and Food Research

SN - 1613-4125

IS - 9

ER -

Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this