Abstract
Scope: Only a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Methods and results: We analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to
Original language | English |
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Pages (from-to) | 1641-1650 |
Number of pages | 10 |
Journal | Molecular Nutrition and Food Research |
Volume | 59 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sep 1 2015 |
Keywords
- Allium vegetables
- Diet
- Garlic
- Head and Neck Neoplasms
- Onion
ASJC Scopus subject areas
- Food Science
- Biotechnology