Relation of Echocardiographic Epicardial Fat Thickness and Myocardial Fat

Alexis Elias Malavazos, Giovanni Di Leo, Francesco Secchi, Eleonora Norma Lupo, Giada Dogliotti, Calin Coman, Lelio Morricone, Massimiliano Marco Corsi, Francesco Sardanelli, Gianluca Iacobellis

Research output: Contribution to journalArticlepeer-review


Epicardial and myocardial fats increase with degree of visceral adiposity and possibly contribute to obesity-associated cardiac changes. Echocardiographic epicardial fat thickness is a new and independent marker of visceral adiposity. The aim of this study was to test whether echocardiographic epicardial fat is related to myocardial fat. Twenty consecutive Caucasian men (body mass index 30.5 ± 2 kg/m2, 42 ± 7 years of age) underwent transthoracic echocardiography for epicardial fat thickness, morphologic and diastolic parameter measurements, hydrogen-1 magnetic resonance spectroscopy for myocardial fat quantification, and magnetic resonance imaging for epicardial fat volume estimation. Hydrogen-1 magnetic resonance spectroscopic myocardial fat content, magnetic resonance imaging of epicardial fat volume, and echocardiographic epicardial fat thickness range varied from 0.5% to 31%, 4.5 to 43 ml, and 3 to 15 mm, respectively. Myocardial fat content showed a statistically significant correlation with echocardiographic epicardial fat thickness (r = 0.79, p

Original languageEnglish
Pages (from-to)1831-1835
Number of pages5
JournalThe American Journal of Cardiology
Issue number12
Publication statusPublished - Jun 15 2010

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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