Relations between respiratory symptoms and spirometric values in young adults

The European community respiratory health study

Jordi Sunyer, Xavier Basagaña, Josep Roca, Isabel Urrutia, Angels Jaen, Josep M. Antó, Peter Burney, S. Chinn, C. Luczynska, D. Jarvis, E. Lai, M. Abramson, J. Kutin, P. Vermeire, F. van Bastelaer, J. Bousquet, F. Neukirch, R. Liard, I. Pin, C. Pison & 58 others A. Taytard, H. Magnussen, D. Nowak, H. E. Wichmann, J. Heinrich, T. Gislason, D. Gislason, J. Prichard, S. Allwright, D. Macleod, M. Bugiani, C. Bucca, C. Romano, R. de Marco, V. Lo Cascio, C. Campello, A. Marinoni, I. Cerveri, L. Casali, B. Rijcken, A. Kremer, J. Crane, S. Lewis, A. Gulsvik, E. Omenaas, J. Anto, A. Jaen, J. Roca, M. Kogevinas, N. Muniozguren, I. Urrutia, A. Capelastegui, J. Martinez-Moratalla, E. Almar, J. Maldonado, A. Pereira, J. Sánchez, F. Payo, I. Huerta, G. Boman, C. Janson, E. Bjornsson, L. Rosenhall, E. Norrman, B. Lundback, N. Lindholm, P. Plasche, U. Ackermann-Liebrich, N. Künzli, A. Perruchoud, M. Burr, J. Layzqll, R. Hall, B. Harrison, J. Stark, S. Buist, W. Vollmer, M. Osborne

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We aim to assess whether respiratory symptoms are associated with lung function in young adults, and whether any such relation is similar in those with asthma, in men and women, and in different countries. Study participants (aged 20-44 years) were randomly selected from the general population in 35 centres in 15 countries as part of the European Community Respiratory Health Study. In all, 12,541 subjects (47%) completed a respiratory symptoms questionnaire and spirometry, metacholine challenge and immunoglobulin E tests. Indicators of diagnosed asthma showed the largest association with airways obstruction (FEV1-maximal 1-s forced expiratory volume/forced vital capacity-FVC1/FVC ratios were greater or equal to 70%, wheezing or shortness of breath was associated with lower FEV1levels (-211 ml in men and -169 ml in women (P1levels. Findings were homogeneous across all centres. These results suggest that lung diseases that cause wheezing are generally associated with impaired lung function.

Original languageEnglish
Pages (from-to)1025-1033
Number of pages9
JournalRespiratory Medicine
Volume98
Issue number10
DOIs
Publication statusPublished - 2004

Fingerprint

Respiratory Sounds
European Union
Young Adult
Asthma
Lung
Spirometry
Vital Capacity
Health
Forced Expiratory Volume
Airway Obstruction
Dyspnea
Immunoglobulin E
Lung Diseases
Population
Surveys and Questionnaires

Keywords

  • Asthma
  • Bronchial obstruction
  • Factor analysis
  • FEV<inf>1</inf>
  • FVC
  • Lung function
  • Respiratory symptoms
  • Wheezing

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Relations between respiratory symptoms and spirometric values in young adults : The European community respiratory health study. / Sunyer, Jordi; Basagaña, Xavier; Roca, Josep; Urrutia, Isabel; Jaen, Angels; Antó, Josep M.; Burney, Peter; Chinn, S.; Luczynska, C.; Jarvis, D.; Lai, E.; Abramson, M.; Kutin, J.; Vermeire, P.; van Bastelaer, F.; Bousquet, J.; Neukirch, F.; Liard, R.; Pin, I.; Pison, C.; Taytard, A.; Magnussen, H.; Nowak, D.; Wichmann, H. E.; Heinrich, J.; Gislason, T.; Gislason, D.; Prichard, J.; Allwright, S.; Macleod, D.; Bugiani, M.; Bucca, C.; Romano, C.; de Marco, R.; Lo Cascio, V.; Campello, C.; Marinoni, A.; Cerveri, I.; Casali, L.; Rijcken, B.; Kremer, A.; Crane, J.; Lewis, S.; Gulsvik, A.; Omenaas, E.; Anto, J.; Jaen, A.; Roca, J.; Kogevinas, M.; Muniozguren, N.; Urrutia, I.; Capelastegui, A.; Martinez-Moratalla, J.; Almar, E.; Maldonado, J.; Pereira, A.; Sánchez, J.; Payo, F.; Huerta, I.; Boman, G.; Janson, C.; Bjornsson, E.; Rosenhall, L.; Norrman, E.; Lundback, B.; Lindholm, N.; Plasche, P.; Ackermann-Liebrich, U.; Künzli, N.; Perruchoud, A.; Burr, M.; Layzqll, J.; Hall, R.; Harrison, B.; Stark, J.; Buist, S.; Vollmer, W.; Osborne, M.

In: Respiratory Medicine, Vol. 98, No. 10, 2004, p. 1025-1033.

Research output: Contribution to journalArticle

Sunyer, J, Basagaña, X, Roca, J, Urrutia, I, Jaen, A, Antó, JM, Burney, P, Chinn, S, Luczynska, C, Jarvis, D, Lai, E, Abramson, M, Kutin, J, Vermeire, P, van Bastelaer, F, Bousquet, J, Neukirch, F, Liard, R, Pin, I, Pison, C, Taytard, A, Magnussen, H, Nowak, D, Wichmann, HE, Heinrich, J, Gislason, T, Gislason, D, Prichard, J, Allwright, S, Macleod, D, Bugiani, M, Bucca, C, Romano, C, de Marco, R, Lo Cascio, V, Campello, C, Marinoni, A, Cerveri, I, Casali, L, Rijcken, B, Kremer, A, Crane, J, Lewis, S, Gulsvik, A, Omenaas, E, Anto, J, Jaen, A, Roca, J, Kogevinas, M, Muniozguren, N, Urrutia, I, Capelastegui, A, Martinez-Moratalla, J, Almar, E, Maldonado, J, Pereira, A, Sánchez, J, Payo, F, Huerta, I, Boman, G, Janson, C, Bjornsson, E, Rosenhall, L, Norrman, E, Lundback, B, Lindholm, N, Plasche, P, Ackermann-Liebrich, U, Künzli, N, Perruchoud, A, Burr, M, Layzqll, J, Hall, R, Harrison, B, Stark, J, Buist, S, Vollmer, W & Osborne, M 2004, 'Relations between respiratory symptoms and spirometric values in young adults: The European community respiratory health study', Respiratory Medicine, vol. 98, no. 10, pp. 1025-1033. https://doi.org/10.1016/j.rmed.2004.01.013
Sunyer, Jordi ; Basagaña, Xavier ; Roca, Josep ; Urrutia, Isabel ; Jaen, Angels ; Antó, Josep M. ; Burney, Peter ; Chinn, S. ; Luczynska, C. ; Jarvis, D. ; Lai, E. ; Abramson, M. ; Kutin, J. ; Vermeire, P. ; van Bastelaer, F. ; Bousquet, J. ; Neukirch, F. ; Liard, R. ; Pin, I. ; Pison, C. ; Taytard, A. ; Magnussen, H. ; Nowak, D. ; Wichmann, H. E. ; Heinrich, J. ; Gislason, T. ; Gislason, D. ; Prichard, J. ; Allwright, S. ; Macleod, D. ; Bugiani, M. ; Bucca, C. ; Romano, C. ; de Marco, R. ; Lo Cascio, V. ; Campello, C. ; Marinoni, A. ; Cerveri, I. ; Casali, L. ; Rijcken, B. ; Kremer, A. ; Crane, J. ; Lewis, S. ; Gulsvik, A. ; Omenaas, E. ; Anto, J. ; Jaen, A. ; Roca, J. ; Kogevinas, M. ; Muniozguren, N. ; Urrutia, I. ; Capelastegui, A. ; Martinez-Moratalla, J. ; Almar, E. ; Maldonado, J. ; Pereira, A. ; Sánchez, J. ; Payo, F. ; Huerta, I. ; Boman, G. ; Janson, C. ; Bjornsson, E. ; Rosenhall, L. ; Norrman, E. ; Lundback, B. ; Lindholm, N. ; Plasche, P. ; Ackermann-Liebrich, U. ; Künzli, N. ; Perruchoud, A. ; Burr, M. ; Layzqll, J. ; Hall, R. ; Harrison, B. ; Stark, J. ; Buist, S. ; Vollmer, W. ; Osborne, M. / Relations between respiratory symptoms and spirometric values in young adults : The European community respiratory health study. In: Respiratory Medicine. 2004 ; Vol. 98, No. 10. pp. 1025-1033.
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AU - Sunyer, Jordi

AU - Basagaña, Xavier

AU - Roca, Josep

AU - Urrutia, Isabel

AU - Jaen, Angels

AU - Antó, Josep M.

AU - Burney, Peter

AU - Chinn, S.

AU - Luczynska, C.

AU - Jarvis, D.

AU - Lai, E.

AU - Abramson, M.

AU - Kutin, J.

AU - Vermeire, P.

AU - van Bastelaer, F.

AU - Bousquet, J.

AU - Neukirch, F.

AU - Liard, R.

AU - Pin, I.

AU - Pison, C.

AU - Taytard, A.

AU - Magnussen, H.

AU - Nowak, D.

AU - Wichmann, H. E.

AU - Heinrich, J.

AU - Gislason, T.

AU - Gislason, D.

AU - Prichard, J.

AU - Allwright, S.

AU - Macleod, D.

AU - Bugiani, M.

AU - Bucca, C.

AU - Romano, C.

AU - de Marco, R.

AU - Lo Cascio, V.

AU - Campello, C.

AU - Marinoni, A.

AU - Cerveri, I.

AU - Casali, L.

AU - Rijcken, B.

AU - Kremer, A.

AU - Crane, J.

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AU - Omenaas, E.

AU - Anto, J.

AU - Jaen, A.

AU - Roca, J.

AU - Kogevinas, M.

AU - Muniozguren, N.

AU - Urrutia, I.

AU - Capelastegui, A.

AU - Martinez-Moratalla, J.

AU - Almar, E.

AU - Maldonado, J.

AU - Pereira, A.

AU - Sánchez, J.

AU - Payo, F.

AU - Huerta, I.

AU - Boman, G.

AU - Janson, C.

AU - Bjornsson, E.

AU - Rosenhall, L.

AU - Norrman, E.

AU - Lundback, B.

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AU - Plasche, P.

AU - Ackermann-Liebrich, U.

AU - Künzli, N.

AU - Perruchoud, A.

AU - Burr, M.

AU - Layzqll, J.

AU - Hall, R.

AU - Harrison, B.

AU - Stark, J.

AU - Buist, S.

AU - Vollmer, W.

AU - Osborne, M.

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N2 - We aim to assess whether respiratory symptoms are associated with lung function in young adults, and whether any such relation is similar in those with asthma, in men and women, and in different countries. Study participants (aged 20-44 years) were randomly selected from the general population in 35 centres in 15 countries as part of the European Community Respiratory Health Study. In all, 12,541 subjects (47%) completed a respiratory symptoms questionnaire and spirometry, metacholine challenge and immunoglobulin E tests. Indicators of diagnosed asthma showed the largest association with airways obstruction (FEV1-maximal 1-s forced expiratory volume/forced vital capacity-FVC1/FVC ratios were greater or equal to 70%, wheezing or shortness of breath was associated with lower FEV1levels (-211 ml in men and -169 ml in women (P1levels. Findings were homogeneous across all centres. These results suggest that lung diseases that cause wheezing are generally associated with impaired lung function.

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KW - Asthma

KW - Bronchial obstruction

KW - Factor analysis

KW - FEV<inf>1</inf>

KW - FVC

KW - Lung function

KW - Respiratory symptoms

KW - Wheezing

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